Blog
About
Search
Advanced search

2,528
views
14
references
 Top references
0
cited by
 Most cited
    
1 reviews
 Review
0
comments
 Comment
1
recommends
+1 Recommend
1 collections
    58
    shares
      35,370
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Synthesis of quinolinequinone derivatives and related carbocyclic compounds

      Read this article at

      ScienceOpen
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Palladium-catalyzed Buchwald-Hartwig aminations of various quinolinequinone derivatives give excellent yields of novel 6-arylamino derivatives of the disubstituted quinolinequinones and 3-arylamino derivatives of the corresponding naphthoquinones. The precursor quinolinequinones are prepared in a three-step sequence from 8-hydroxyquinoline. The transition-metal-catalyzed arylations of 6,7-dibromo-5,8-quinolinequinone, 6,7-dichloro-5,8-quinolinequinone and 2,3-dichloro-1,4-naphthoquinone are reported for the first time and offer fast and easy access to their derivatives.

          Related collections

          Most cited references 14

          • Record: found
          • Abstract: found
          • Article: not found

          Expanding Pd-catalyzed C-N bond-forming processes: the first amidation of aryl sulfonates, aqueous amination, and complementarity with Cu-catalyzed reactions.

           Stephen Buchwald,  Xiaohua Huang,  Artis Klapars … (2003)
          The first general method for the Pd-catalyzed amination of aryl tosylates and benzenesulfonates was developed utilizing ligand 1, which belongs to a new generation of biaryl monophosphine ligands. In addition, the new catalyst system for the first time enables amidation of aryl arenesulfonates and aqueous amination protocols that do not necessitate the use of cosolvents. The substrate scope has been significantly expanded to include aryl halides containing primary amides and free carboxylic acid groups. In the case of multifunctional substrates, the Pd-catalyzed amination can provide selectivity that is complementary to the Cu-catalyzed C-N bond-forming processes.
          Article 0 comments Cited 66 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Palladium-catalyzed formation of carbon-nitrogen bonds. Reaction intermediates and catalyst improvements in the hetero cross-coupling of aryl halides and tin amides

             Frederic Paul,  Joe Patt,  John Hartwig (1994)
            Article 0 comments Cited 58 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Use of tunable ligands allows for intermolecular Pd-catalyzed C--O bond formation.

               Andrei V Vorogushin,  Xiaohua Huang,  Stephen Buchwald (2005)
              Bulky biaryl phosphine ligands facilitate Pd-catalyzed C-O coupling reactions of aryl halides with primary and secondary alcohols by promoting reductive elimination at the expense of beta-hydride elimination. The key to their success is the ability to match the size of the ligand to that of the combination of substrates. The efficient coupling of a number of unactivated aryl chlorides and bromides with cyclic and acyclic secondary alcohols was achieved. This included the coupling of allylic alcohols for the first time in a Pd-catalyzed coupling process.
              Article 0 comments Cited 32 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Affiliations
                [1 ]Department of Pure and Industrial Chemistry, University of Nigeria, Nsukka, Nigeria
                [2 ]School of Chemistry, Cardiff University, Park Place, Main Building, Cardiff CF10 3AT, UK
                Author notes
                [* ]Corresponding author's e-mail address: wirth@ 123456cf.ac.uk
                Contributors
                Journal
                Journal ID (publisher-id): SOR-CHEM
                Title: ScienceOpen Research
                Publisher: ScienceOpen
                ISSN (Electronic): 2199-1006
                Publication date: 19 December 2014
                Volume: 0 (ID: 4e3315b4-59e4-49b2-b49e-078ceb9cce92 )
                Issue: 0
                Pages: 1-6
                Publisher ID: 2302:XE
                DOI: 10.14293/S2199-1006.1.SOR-CHEM.AALL9P.v1
                Copyright statement: © 2014 S.A. Egu et al.

                License:

                This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

                Counts
                Figures: 14, Tables: 3, References: 16, Pages: 6
                Product
                Categories
                Subject: Original article

                Data availability:

                ScienceOpen disciplines: Chemistry

                Keywords: Pd catalysis, amination, quinolidinequinones, Buchwald-Hartwig reaction

                Comments

                Comment on this article