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      Development of a highly selective fluorescence probe for hydrogen sulfide.

      Journal of the American Chemical Society
      American Chemical Society (ACS)

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          Abstract

          Hydrogen sulfide (H(2)S) has recently been identified as a biological response modifier. Here, we report the design and synthesis of a novel fluorescence probe for H(2)S, HSip-1, utilizing azamacrocyclic copper(II) ion complex chemistry to control the fluorescence. HSip-1 showed high selectivity and high sensitivity for H(2)S, and its potential for biological applications was confirmed by employing it for fluorescence imaging of H(2)S in live cells.

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          Journal
          10.1021/ja207851s
          21999237

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