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<h5 class="title" id="d450548e121">Purpose</h5>
<p id="P1">To describe frequency of postoperative diplopia after strabismus surgery
in nondiplopic
adults with childhood-onset strabismus and to report health-related quality-of-life
(HRQOL) outcomes.
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<h5 class="title" id="d450548e126">Methods</h5>
<p id="P2">We prospectively enrolled 79 adults with no diplopia in any gaze who had
childhood-onset
strabismus and were scheduled for strabismus surgery. Diplopia was assessed preoperatively
and at 6 weeks and 1 year postoperatively using a standardized diplopia questionnaire
with 5 response options in 7 gaze positions. HRQOL was assessed using the Adult Strabismus-20
(AS-20) questionnaire, with self-perception, interactions, reading function, and general
function domains.
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<h5 class="title" id="d450548e131">Results</h5>
<p id="P3">Constant diplopia in straight-ahead distance and reading gaze occurred
in 1 patient
(1% [95% CI, 0%-7%] at 6 weeks and 2% [95% CI, 0%-10%] at 1 year). Regarding the rate
of any diplopia (including rarely) in any gaze, 15 of 78 patients (19%) reported diplopia
at 6 weeks, of whom 13 had diplopia in straight-ahead distance gaze; 8 (10%), in reading
gaze. At 1 year, 8 of 51 patients (16%) reported at least rare diplopia in any gaze,
of whom 7 had diplopia in straight-ahead distance gaze and 4 (8%) in reading gaze.
Mean AS-20 scores improved at 1 year overall (by 32, 19, 14, and 15 points, resp.,
per domain) and for the 8 diplopic patients (by 21, 13, 16, and 11 points).
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<h5 class="title" id="d450548e136">Conclusions</h5>
<p id="P4">In adults with nondiplopic strabismus, constant postoperative diplopia
is rare, although
the rate of intermittent diplopia is higher. Even when postoperative diplopia occurs,
HRQOL often improves.
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