Effect of symptom severity on efficacy and safety of aripiprazole adjunctive to antidepressant monotherapy in major depressive disorder: a pooled analysis.

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Abstract

There is a paucity of evidence for outcome predictors in patients with major depressive disorder (MDD) not responding to initial antidepressant therapy (ADT). This post-hoc analysis evaluated whether MDD severity affects response to adjunctive aripiprazole.

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Journal ID (iso-abbrev): J Affect Disord

Title: Journal of affective disorders

ISSN (Electronic): 1573-2517

ISSN (Print): 0165-0327

Publication date (Electronic): Jun 2014

Volume: 162

Affiliations

[1 ] Yale School of Medicine, New Haven, CT, USA.

[2 ] Otsuka America Pharmaceutical, Inc., Princeton, NJ, USA.

[3 ] Otsuka Pharmaceutical Development and Commercialization, Princeton, NJ, USA.

[4 ] Bristol-Myers Squibb, Plainsboro, NJ, USA.

[5 ] Bristol-Myers Squibb, Wallingford, CT, USA.

[6 ] Yale School of Medicine, New Haven, CT, USA; Bristol-Myers Squibb, Wallingford, CT, USA.

[7 ] Department of Psychiatry, University of California, San Francisco, 401 Parnassus Avenue, San Francisco, CA 94143, USA. Electronic address: CraigN@lppi.ucsf.edu.

Article

Publisher Item ID: S0165-0327(14)00119-0

DOI: 10.1016/j.jad.2014.03.017

PubMed ID: 24766999

SO-VID: 4e5e5d6c-9fe8-46a9-9343-3b6fa2dfa61f

History

Keywords: Antidepressant therapy,Augmentation,Major depressive disorder,Symptom severity

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Keywords: Antidepressant therapy, Augmentation, Major depressive disorder, Symptom severity

Effect of symptom severity on efficacy and safety of aripiprazole adjunctive to antidepressant monotherapy in major depressive disorder: a pooled analysis.

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