9
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Factores asociados a la duración del hemofiltro en técnicas continuas de depuración extracorpórea en el paciente ingresado en cuidados intensivos Translated title: Factors associated with haemofilter duration in continuous extracorporeal clearance techniques in intensive care unit patients

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Resumen Objetivos: Determinar la vida media de los hemofiltros en el paciente crítico ingresado en la unidad de cuidados intensivos y los principales factores asociados a su duración. Metodología: Estudio descriptivo observacional transversal, realizado en una Unidad de Cuidados Intensivos de adultos polivalente. Se estudiaron los hemofiltros colocados en 67 pacientes mayores de 18 años, entre enero y noviembre de 2019. Variables: edad, sexo, peso, unidad de ingreso, velocidad de flujo sanguíneo, fracción de filtrado, débito horario, anticoagulación del sistema, tiempo de tromboplastina activada (TTPA), indicación médica de la terapia, causa de la retirada, localización del catéter, hora de inicio y finalización de la terapia. Resultados: La edad media de los pacientes fue de 62,66 años (±9,95), 81 (71,64%) hombres. Se analizaron un total de 238 hemofiltros con una vida media de 26,28 horas (±22,8). El 80,1 % de los catéteres fueron femorales, el 19% yugulares y el 0,8% subclavios. Se empleó como terapia de anticoagulación, heparina sódica en un 45,8%, citratos en el 20,2% y en un 34% no se utilizó anticoagulación. La velocidad media de flujo sanguíneo fue de 190,08 ml/min (±53,48). Se encontró relación estadística entre las variables flujo sanguíneo (rs=0,208; p=0,001), localización del catéter y duración del hemofiltro (p=0,03). Conclusiones: La vida media del hemofiltro fue de 26 horas. La velocidad del flujo sanguíneo y localización del catéter son factores que repercuten en la duración del hemofiltro.

          Translated abstract

          Abstract Objectives: To determine the half-life of haemofilters in critically ill patients admitted to the intensive care unit (ICU) and the main factors associated with their duration. Methodology: Cross-sectional observational descriptive study conducted in a polyvalent adult intensive care unit. The haemofilters placed in 67 patients over 18 years of age between January and November 2019 were studied. Variables: age, sex, weight, admission unit, blood flow velocity, filtration fraction, hourly debit, system anticoagulation, activated thromboplastin time (APTT), medical indication for therapy, cause of withdrawal, catheter location, start and end time of therapy. Results: The mean age of the patients was 62.66 years (±9.95), 81 (71.64%) men. A total of 238 haemofilters with a mean lifetime of 26.28 hours (±22.8) were analysed. Femoral catheters accounted for 80.1 %, jugular catheters for 19 % and subclavian catheters for 0.8 %. Sodium heparin was used as anticoagulation therapy in 45.8 %, citrates in 20.2 % and no anticoagulation in 34 %. Mean blood flow velocity was 190.08 ml/min (±53.48). A statistical relationship was found between the variables blood flow (rs=0.208; p=0.001), catheter location and haemofilter duration (p=0.03). Conclusions: The half-life of the haemofilter was 26 hours. Blood flow velocity and catheter location are factors that affect the duration of the haemofilter

          Related collections

          Most cited references35

          • Record: found
          • Abstract: found
          • Article: not found

          A comparison of the RIFLE and AKIN criteria for acute kidney injury in critically ill patients.

          The Acute Dialysis Quality Initiative Group has published a consensus definition/classification system for acute kidney injury (AKI) termed the RIFLE criteria. The Acute Kidney Injury Network (AKIN) group has recently proposed modifications to this system. It is currently unknown whether there are advantages between these criteria. We interrogated the Australian New Zealand Intensive Care Society (ANZICS) Adult Patient Database (APD) for all adult admissions to 57 ICUs from 1 January 2000 to 31 December 2005. We compared the performance of the RIFLE and AKIN criteria for diagnosis and classification of AKI and for robustness of hospital mortality. We included 120 123 critically ill patients, of which 27.8% had a primary diagnosis of sepsis. We found only small differences (<1%) in the number of patients classified as having some degree of kidney injury using either the AKIN or RIFLE definition or classification systems. AKIN slightly increased the number of patients classified as Stage I injury (category R in RIFLE) (from 16.2 to 18.1%) but decreased the number of patients classified as having Stage II injury (category I in RIFLE) (13.6% versus 10.1%). The area under the ROC curve for hospital mortality was 0.66 for RIFLE and 0.67 for AKIN in all patients and it was 0.65 for both in septic patients. Compared to the RIFLE criteria, the AKIN criteria do not materially improve the sensitivity, robustness and predictive ability of the definition and classification of AKI in the first 24 h after admission to ICU.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: found
            Is Open Access

            Non anti-coagulant factors associated with filter life in continuous renal replacement therapy (CRRT): a systematic review and meta-analysis

            Background Optimising filter life and performance efficiency in continuous renal replacement therapy has been a focus of considerable recent research. Larger high quality studies have predominantly focussed on optimal anticoagulation however CRRT is complex and filter life is also affected by vascular access, circuit and management factors. We performed a systematic search of the literature to identify and quantify the effect of vascular access, circuit and patient factors that affect filter life and presented the results as a meta-analysis. Methods A systematic review and meta-analysis was performed by searching Pubmed (MEDLINE) and Ovid EMBASE libraries from inception to 29th February 2016 for all studies with a comparator or independent variable relating to CRRT circuits and reporting filter life. Included studies documented filter life in hours with a comparator other than anti-coagulation intervention. All studies comparing anticoagulation interventions were searched for regression or hazard models pertaining to other sources of variation in filter life. Results Eight hundred nineteen abstracts were identified of which 364 were selected for full text analysis. 24 presented data on patient modifiers of circuit life, 14 on vascular access modifiers and 34 on circuit related factors. Risk of bias was high and findings are hypothesis generating. Ranking of vascular access site by filter longevity favours: tunnelled semi-permanent catheters, femoral, internal jugular and subclavian last. There is inconsistency in the difference reported between femoral and jugular catheters. Amongst published literature, modality of CRRT consistently favoured continuous veno-venous haemodiafiltration (CVVHD-F) with an associated 44% lower failure rate compared to CVVH. There was a trend favouring higher blood flow rates. There is insufficient data to determine advantages of haemofilter membranes. Patient factors associated with a statistically significant worsening of filter life included mechanical ventilation, elevated SOFA or LOD score, elevations in ionized calcium, elevated platelet count, red cell transfusion, platelet factor 4 (PF-4) antibodies, and elevated fibrinogen. Majority of studies are observational or report circuit factors in sub-analysis. Risk of bias is high and findings require targeted investigations to confirm. Conclusion The interaction of patient, pathology, anticoagulation, vascular access, circuit and staff factors contribute to CRRT filter life. There remains an ambiguity from published data as to which site and side should be the first choice for vascular access placement and what interaction this has with patient factors and timing. Early consideration of tunnelled semi-permanent access may provide optimal filter life if longer periods of CRRT are anticipated. There remains an absence of robust evidence outside of anti-coagulation strategies despite over 20 years of therapy delivery however trends favour CVVHD-F over CVVH.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found

              Handling Continuous Renal Replacement Therapy-Related Adverse Effects in Intensive Care Unit Patients: The Dialytrauma Concept

              Continuous renal replacement therapy (CRRT) is increasingly used for the management of critically ill patients. As a consequence, the incidence of complications that accompany CRRT is also rising. However, a standardized approach for preventing or minimizing these adverse events is lacking. Dialytrauma is a newly proposed concept that encompasses all harmful adverse events related to CRRT while providing a framework for prevention or, at the least, early recognition of these events in order to attenuate the consequences. A mainstay of this approach is the utilization of a dedicated checklist for improving CRRT quality and patient safety. In this context, we discuss the most important adverse effects of CRRT and review current strategies to minimize them.
                Bookmark

                Author and article information

                Journal
                enefro
                Enfermería Nefrológica
                Enferm Nefrol
                Sociedad Española de Enfermería Nefrológica (Madrid, Madrid, Spain )
                2254-2884
                2255-3517
                December 2021
                : 24
                : 4
                : 389-397
                Affiliations
                [1] Palma orgnameHospital Universitari Son Espases orgdiv1Unidad de Cuidados Intensivos Spain
                [2] orgnameSociedad Española de Enfermería Intensiva y Unidades Coronarias (SEEIUC) orgdiv1Grupo de trabajo en Técnicas Extracorpóreas Spain
                [3] orgnameCronicitat i evidències en salut (CurES-IdISBa) orgdiv1Grup d'Investigació en Cures Spain
                Article
                S2254-28842021000400006 S2254-2884(21)02400400006
                10.37551/s2254-28842021033
                4e7d8309-ab8b-493f-8e3b-13258d88619b

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 28 February 2021
                : 26 October 2021
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 35, Pages: 9
                Product

                SciELO Spain

                Categories
                Originales

                haemofiltration,critical care,anticoagulants,vascular access device,blood flow velocity,hemofiltración,cuidados críticos,anticoagulantes,dispositivo de acceso vascular,velocidad del flujo sanguíneo

                Comments

                Comment on this article