99
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Transcriptome Profiling of Wheat Seedlings following Treatment with Ultrahigh Diluted Arsenic Trioxide

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Plant systems are useful research tools to address basic questions in homeopathy as they make it possible to overcome some of the drawbacks encountered in clinical trials (placebo effect, ethical issues, duration of the experiment, and high costs). The objective of the present study was to test the hypothesis whether 7-day-old wheat seedlings, grown from seeds either poisoned with a sublethal dose of As 2O 3 or unpoisoned, showed different significant gene expression profiles after the application of ultrahigh diluted As 2O 3 (beyond Avogadro's limit) compared to water (control). The results provided evidence for a strong gene modulating effect of ultrahigh diluted As 2O 3 in seedlings grown from poisoned seeds: a massive reduction of gene expression levels to values comparable to those of the control group was observed for several functional classes of genes. A plausible hypothesis is that ultrahigh diluted As 2O 3 treatment induced a reequilibration of those genes that were upregulated during the oxidative stress by bringing the expression levels closer to the basal levels normally occurring in the control plants.

          Related collections

          Most cited references80

          • Record: found
          • Abstract: not found
          • Article: not found

          Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Role of plant heat-shock proteins and molecular chaperones in the abiotic stress response.

              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              BRASSINOSTEROIDS: Essential Regulators of Plant Growth and Development.

              Brassinosteroids (BRs) are growth-promoting natural products found at low levels in pollen, seeds, and young vegetative tissues throughout the plant kingdom. Detailed studies of BR biosynthesis and metabolism, coupled with the recent identification of BR-insensitive and BR-deficient mutants, has greatly expanded our view of steroids as signals controlling plant growth and development. This review examines the microchemical and molecular genetic analyses that have provided convincing evidence for an essential role of BRs in diverse developmental programs, including cell expansion, vascular differentiation, etiolation, and reproductive development. Recent advances relevant to the molecular mechanisms of BR-regulated gene expression and BR signal transduction are also discussed.
                Bookmark

                Author and article information

                Journal
                Evid Based Complement Alternat Med
                Evid Based Complement Alternat Med
                ECAM
                Evidence-based Complementary and Alternative Medicine : eCAM
                Hindawi Publishing Corporation
                1741-427X
                1741-4288
                2014
                27 November 2014
                27 November 2014
                : 2014
                : 851263
                Affiliations
                1Department of Agricultural Sciences, University of Bologna, Viale Fanin 44, 40127 Bologna, Italy
                2Department of Public Health and Infectious Diseases, “La Sapienza” University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
                3Italian National Health System, Lombardy District, “Azienda Sanitaria Locale” Milan, Corso Italia 19, 20122 Milan, Italy
                Author notes

                Academic Editor: Kuttulebbai N. S. Sirajudeen

                Author information
                http://orcid.org/0000-0003-3630-5861
                http://orcid.org/0000-0002-4686-4504
                http://orcid.org/0000-0003-2722-8390
                Article
                10.1155/2014/851263
                4265686
                25525452
                4f6158ac-1add-46b3-a797-dbf2f04b26b2
                Copyright © 2014 Ilaria Marotti et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 7 August 2014
                : 29 October 2014
                : 30 October 2014
                Categories
                Research Article

                Complementary & Alternative medicine
                Complementary & Alternative medicine

                Comments

                Comment on this article