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      First CytoJournal Peer-Reviewer's Retreat in 2006 – Open access, peer-review, and impact factor

      editorial
      1 , , 2 , 3
      CytoJournal
      BioMed Central

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          Abstract

          CytoJournal organized its first Peer-Reviewer's Retreat of 2006 during the United States and Canadian Academy of Pathology Annual Meeting at Atlanta on Feb 12, 2006. The major topics discussed were open access, peer review, and impact factors. Representative participants volunteered to join the task force to prepare an instructional guide for peer-reviewing cytopathology manuscripts. Concern about the impact factor for CytoJournal was discussed. A feedback to its readers and authors was recommended. Impact factor calculation needs at least three years of journal statistics. It is only possible after two years from the time a journal is first accepted by Thomson-ISI for citation tracking. CytoJournal is still too new for an impact factor to be calculated. However, general progress of CytoJournal suggests an encouraging pattern for high impact factor.

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          Optimization of an immunostaining protocol for the rapid intraoperative evaluation of melanoma sentinel lymph node imprint smears with the 'MCW melanoma cocktail'

          Background In the management of cutaneous melanoma, it is desirable to complete the regional lymphadenectomy during the initial surgical procedure for wide excision of biopsy site and sentinel lymph node (SLN) biopsy. In this study, we optimized and evaluated a rapid 17 minutes immunostaining protocol. The discriminatory immunostaining pattern associated with the 'MCW Melanoma Cocktail' (mixture of Melan- A, MART- 1, and tyrosinase) facilitated the feasibility of intraoperative evaluation of imprint smears of SLNs for melanoma metastases. Methods Imprint smears of 51 lymph nodes from 25 cases (48 SLNs and 3 non-SLNs, 1 to 4 SLNs/case) of cutaneous melanoma were evaluated. Results Sixteen percent, 8/51 lymph nodes (28%, 7/25 cases) were positive for melanoma metastases in immunostained permanent sections with the 'MCW melanoma cocktail'. All of these melanoma metastases, except 1 SLN from 1 case, were also detected in rapidly immunostained wet-fixed and air-dried smears (rehydrated in saline and postfixed in alcoholic formalin). The cytomorphology was superior in air-dried smears, which were rehydrated in saline and postfixed in alcoholic formalin. Wet-fixed smears frequently showed air-drying artifacts, which lead to the focal loss of immunostaining. None of the 5 SLNs from 5 cases exhibiting capsular nevi showed a false positive result with immunostained imprint smears. Conclusions Melanoma metastases can be detected intraoperatively in both air-dried smears and wet-fixed smears immunostained with the MCW Melanoma cocktail. Air-dried smears rehydrated in saline and postfixed in alcoholic formalin provide superior results and many practical benefits.
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            The agony and the ecstasy: The history and Meaning of the journal impact factor

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              CytoJournal joins 'open access' philosophy

              Welcome to CytoJournal! We would like to introduce you to your journal, one that is run by and for the scientific cytopathology community with incontestable benefits of Open Access, and support from Cytopathology Foundation, Inc. CytoJournal is a peer-reviewed, PubMed indexed, online journal, publishing research in the field of cytopathology and related areas, with world wide free access. Authors submitting to CytoJournal retain the copyright to their hard earned work.
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                Author and article information

                Journal
                Cytojournal
                CytoJournal
                BioMed Central (London )
                1742-6413
                2006
                27 March 2006
                : 3
                : 5
                Affiliations
                [1 ]Co-editor-in-Chief, CytoJournal, Medical College of Wisconsin, Milwaukee, WI, USA
                [2 ]Chair- Open-Access advocacy for CytoJournal, University of California, Los Angeles, CA, USA
                [3 ]Co-editor-in-Chief, CytoJournal, Kansas University Medical Center, Kansas City, KS, USA
                Article
                1742-6413-3-5
                10.1186/1742-6413-3-5
                1421433
                16566816
                4fbd8f87-aae0-4966-8eff-ca6486dd1b8c
                Copyright © 2006 Shidham et al; licensee BioMed Central Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 16 March 2006
                : 27 March 2006
                Categories
                Editorial

                Clinical chemistry
                Clinical chemistry

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