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      Survey of 104 MSM before drug uptake of HIV non-occupational post-exposure prophylaxis in Guangxi

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          Objective This survey aims to understand AIDS knowledge, behavioral characteristics, awareness of non- occupational post-exposure prophylaxis (nPEP), and reasons for using nPEP, the possible impact on behavior change after receiving services among 104 men who have sex with men (MSM) prior to drug uptake of nPEP in 2 cities of Guangxi.

          Methods Participants were recruited through community advocacy in Nanning and Liuzhou. A face-to-face questionnaire survey was conducted on MSM who agreed to participate in investigation before taking medication of HIV nPEP. P <0.05 was considered statistically significant, and descriptive analysis was conducted.

          Results AIDS awareness of 104 MSM respondents reached 98.1% (102/104), and 84.6% (88/104) believed that the HIV prevalence was serious among MSM group in the area where they living. In the past six months, no respondents insisted on condom use each time during homosexual activities, and 54.8% (57/104) experienced condoms torn/ slipped or being deliberately pulled out by sexual partners; 64.4% (67/104) had no fixed partners in the last six months. 88.5% (92/104) had heard of nPEP before the survey, univariate analysis indicated that there was statistically significant difference between nPEP awareness and receiving condom promotion/AIDS voluntary counseling & testing as well as peer education in the past year ( P<0.05). 69.2%(72/104) received nPEP since worrying about the probability of HIV infection by the exposure, while 67.3% (72/104) took the service because they did not understand HIV serological status of sexual partners. If received nPEP, only 9.6% (10/104) believed that condom use would decrease, and 15.4% (16/104) thought the number of sexual partners would increase.

          Conclusion Separation between AIDS knowledge and action among MSM requires a comprehensive prevention and control strategy that emphasizes biomedical approaches and behavioral interventions. The role of networks and Non-Governmental Organization (NGO) in nPEP publicity should be highlighted to increase the awareness of nPEP among target population.


          摘要: 目的 分析广西南宁市、柳州市 104 名男男性行为者(men who have sex with men, MSM)在接受艾滋病非职 业暴露后预防(non-occupational post-exposure prophylaxis, nPEP)用药前的相关艾滋病知识掌握情况、行为学特征、 nPEP 知晓度、使用 nPEP 原因及接受服务后对行为改变可能产生的影响等。 方法 在南宁、柳州市通过社区宣传倡导, 现场招募研究对象。对纳入艾滋病非职业暴露后预防并同意在服药前接受调查的 MSM 开展面对面问卷调查。以 P< 0.05 为差异有统计学意义,对资料进行描述性分析。 结果 104 名 MSM 的艾滋病知晓率为 98.1%(102/104);认为所生 活地区的 MSM 人群中 HIV 流行严重的占 84.6%(88/104)。最近半年同性性行为时能每次使用安全套的 0 人,54.8%(57/ 104)经历过安全套意外破裂、脱落或被性伴故意拔套,64.4%(67/104)最近半年内没有固定性伴。88.5%(92/104)调查 前听说过 nPEP,单因素分析发现,最近一年接受过安全套宣传与发放/艾滋病咨询与检测、最近一年接受过同伴教育对 nPEP 知晓差异有统计学意义( P<0.05)。69.2%(72/104)选择 nPEP 因为担心此次暴露会感染 HIV,67.3%(72/104)表示 性伴感染状况未知。若接受 nPEP,仅有 9.6%(10/104)认为安全套使用会减少,15.4%(16/104)认为性伴数会增加。 结论 MSM 存在艾滋病“知信行分离”,需采取生物医学干预技术和行为干预并重的综合性防治策略。重视网络和社 会组织在 nPEP 宣传中的作用,提高人群知晓率。

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          China Tropical Medicine
          China Tropical Medicine (China )
          01 October 2020
          01 October 2020
          : 20
          : 10
          : 933-938
          1Division of HIV/AIDS Control and Prevention, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, Guangxi 530028, China
          Author notes
          *Corresponding author: LAN Guanghua, E-mail: lgh605@
          © 2020 Editorial Department of China Tropical Medicine

          This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See

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