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Determinants and clinical outcome of uptitration of ACE-inhibitors and beta-blockers in patients with heart failure: a prospective European study
W. Ouwerkerk ,
A.A. Voors ,
S.D. Anker ,
J.G. Cleland ,
K. Dickstein ,
G. Filippatos ,
P. van der Harst ,
H.L. Hillege ,
C.C. Lang ,
J.M. ter Maaten ,
L.L. Ng ,
P. Ponikowski ,
N.J Samani ,
D.J. van Veldhuisen ,
F. Zannad ,
M. Metra ,
A.H. Zwinderman
March 11 2017
March 11 2017
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Abstract
Despite clear guidelines recommendations, most patients with heart failure and reduced
ejection-fraction (HFrEF) do not attain guideline-recommended target doses. We aimed
to investigate characteristics and for treatment-indication-bias corrected clinical
outcome of patients with HFrEF that did not reach recommended treatment doses of ACE-inhibitors/Angiotensin
receptor blockers (ARBs) and/or beta-blockers.
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