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      Are industry-funded charities promoting “advocacy-led studies” or “evidence-based science”?: a case study of the International Life Sciences Institute

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          Abstract

          Background

          Industry sponsorship of public health research has received increasing scrutiny, and, as a result, many multinational corporations (MNCs), such as The Coca-Cola Company and Mars Inc., have committed to transparency with regard to what they fund, and the findings of funded research. However, these MNCs often fund charities, both national and international, which then support research and promote industry-favourable policy positions to leaders. We explore whether one industry funded charity, the International Life Sciences Institute (‘ILSI’), is the scientifically objective, non-lobby, internationally-credible body that it suggests it is, so as to aid the international health and scientific communities to judge ILSI’s outputs.

          Methods

          Between June 2015 and February 2018, U.S. Right to Know), a non-profit consumer and public health group, submitted five U.S. state Freedom of Information requests (FOIs) to explore ILSI engagement with industry, policy makers, and/or researchers, which garnered a total of 17,163 pages for analysis. Two researchers explored these documents to assess the activities and conduct of ILSI against its purported objectives.

          Results

          Within the received documents we identified instances of ILSI seeking to influence research, conferences, public messages, and policy, including instances of punishments for ILSI bodies failing to promote industry-favourable messaging. We identified ILSI promoting its agenda with national and international bodies to influence policy and law, causing the World Health Organization to withdraw from official relations with what it now considers a private sector entity.

          Conclusions

          ILSI seeks to influence individuals, positions, and policy, both nationally and internationally, and its corporate members deploy it as a tool to promote their interests globally. Our analysis of ILSI serves as a caution to those involved in global health governance to be wary of putatively independent research groups, and to practice due diligence before relying upon their funded studies and/or engaging in relationship with such groups.

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          Most cited references6

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          Coca-Cola – a model of transparency in research partnerships? A network analysis of Coca - Cola’s research funding (2008–2016)

          Objective To (i) evaluate the extent to which Coca-Cola’s ‘Transparency Lists’ of 218 researchers that it funds are comprehensive; (ii) map all scientific research acknowledging funding from Coca-Cola; (iii) identify those institutions, authors and research topics funded by Coca-Cola; and (iv) use Coca-Cola’s disclosure to gauge whether its funded researchers acknowledge the source of funding. Design Using Web of Science Core Collection database, we retrieved all studies declaring receipt of direct funding from the Coca-Cola brand, published between 2008 and 2016. Using conservative eligibility criteria, we iteratively removed studies and recreated Coca-Cola’s transparency lists using our data. We used network analysis and structural topic modelling to assess the structure, organization and thematic focus of Coca-Cola’s research enterprise, and string matching to evaluate the completeness of Coca-Cola’s transparency lists. Results Three hundred and eighty-nine articles, published in 169 different journals, and authored by 907 researchers, cite funding from The Coca-Cola Company. Of these, Coca-Cola acknowledges funding forty-two authors (<5 %). We observed that the funded research focuses mostly on nutrition and emphasizes the importance of physical activity and the concept of ‘energy balance’. Conclusions The Coca-Cola Company appears to have failed to declare a comprehensive list of its research activities. Further, several funded authors appear to have failed to declare receipt of funding. Most of Coca-Cola’s research support is directed towards physical activity and disregards the role of diet in obesity. Despite initiatives for greater transparency of research funding, the full scale of Coca-Cola’s involvement is still not known.
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            “Always read the small print”: a case study of commercial research funding, disclosure and agreements with Coca-Cola

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                Author and article information

                Contributors
                +44(0)1223760588 , ss775@cam.ac.uk
                gary@usrtk.org
                ls844@cam.ac.uk
                Martin.McKee@lshtm.ac.uk
                david.stuckler@unibocconi.it
                Journal
                Global Health
                Global Health
                Globalization and Health
                BioMed Central (London )
                1744-8603
                3 June 2019
                3 June 2019
                2019
                : 15
                : 36
                Affiliations
                [1 ]ISNI 0000000121885934, GRID grid.5335.0, Department of Politics and International Studies, , University of Cambridge, ; Cambridge, UK
                [2 ]ISNI 0000000121885934, GRID grid.5335.0, Jesus College, ; Jesus Lane, Cambridge, CB58BL UK
                [3 ]U.S. Right to Know, Cambridge, USA
                [4 ]ISNI 0000 0004 0425 469X, GRID grid.8991.9, Department of Public Health and Policy, London School of Hygiene & Tropical Medicine, ; London, UK
                [5 ]ISNI 0000 0001 2165 6939, GRID grid.7945.f, Dondena Research Centre and Department of Policy Analysis and Public Management, , University of Bocconi, ; Milan, Italy
                Author information
                http://orcid.org/0000-0002-1794-7394
                Article
                478
                10.1186/s12992-019-0478-6
                6545704
                31155001
                508b28dc-94cc-45f6-ba35-b9b75e3de57b
                © The Author(s). 2019

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 19 November 2018
                : 8 May 2019
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/100009827, Laura and John Arnold Foundation;
                Categories
                Research
                Custom metadata
                © The Author(s) 2019

                Health & Social care
                international life sciences institute,industry funding,lobbying,advocacy,conflicts of interest

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