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      Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials

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          Abstract

          Current guidelines to treat iron deficiency recommend daily provision of ferrous iron divided through the day to increase absorption. However, daily dosing and split dosing might increase serum hepcidin and decrease iron absorption from subsequent doses. Our study aim was to compare iron absorption from oral iron supplements given on consecutive versus alternate days and given as single morning doses versus twice-daily split dosing.

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          Author and article information

          Journal
          The Lancet Haematology
          The Lancet Haematology
          Elsevier BV
          23523026
          November 2017
          November 2017
          : 4
          : 11
          : e524-e533
          Article
          10.1016/S2352-3026(17)30182-5
          29032957
          509fdc54-49b7-4342-add9-14d162388e1d
          © 2017

          https://www.elsevier.com/tdm/userlicense/1.0/

          http://www.elsevier.com/open-access/userlicense/1.0/

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