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      Central veins in brain lesions visualized with high-field magnetic resonance imaging: a pathologically specific diagnostic biomarker for inflammatory demyelination in the brain.

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          Abstract

          There is no single test that is diagnostic for multiple sclerosis (MS), and existing diagnostic criteria are imperfect. This can lead to diagnostic delay. Some patients require multiple (sometimes invasive) investigations, and extensive clinical follow-up to confirm or exclude a diagnosis of MS. A diagnostic biomarker that is pathologically specific for the inflammatory demyelination in MS could overhaul current diagnostic algorithms.

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          Author and article information

          Journal
          JAMA Neurol
          JAMA neurology
          American Medical Association (AMA)
          2168-6157
          2168-6149
          May 2013
          : 70
          : 5
          Affiliations
          [1 ] Division of Clinical Neurology, Queen's Medical Centre, University of Nottingham, England.
          Article
          1671735
          10.1001/jamaneurol.2013.1405
          23529352
          50ba0184-da32-4913-acf4-20ffee9165ad
          History

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