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      • Record: found
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      Is Open Access

      Uveitis after COVID-19 Vaccination

      case-report
      Author(s): *
      Publication date (Electronic):
      Journal: Case Reports in Ophthalmology
      Publisher: S. Karger AG
      Keywords: COVID-19, Uveitis, Vaccination

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          Abstract

          This report describes a case of acute uveitis following COVID-19 vaccination. A 21-year-old patient was referred to our department for decreased visual acuity and injection of the left eye. Two days prior, the patient received her second dose of the severe acute respiratory syndrome coronavirus 2 vaccine (BNT162b2, Pfizer-BioNTech). On ocular examination, her left eye's best-corrected visual acuity was 20/250, and its intraocular pressure was 16 mm Hg on a noncontact tonometer. Hypopyon, 4+ cells, and flares were observed in the anterior chamber. The patient was diagnosed with acute uveitis. She received topical dexamethasone (0.1%) hourly and systemic prednisone (50 mg/day). After 7 days, her inflammatory symptoms were mostly resolved. COVID-19 vaccination can cause acute anterior uveitis, which is responsive to steroids.

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          Most cited references13

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          A Novel Coronavirus from Patients with Pneumonia in China, 2019

          Na Zhu, Dingyu Zhang, Wenling Wang … (2020)
          Summary In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.)
          Article 0 comments Cited 13203 times – based on 0 reviews     Review now
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            Development of an inactivated vaccine candidate, BBIBP-CorV, with potent protection against SARS-CoV-2

            Hui WANG, Yuntao Zhang, Baoying Huang … (2020)
            Summary The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global public health. The development of a vaccine is urgently needed for the prevention and control of COVID-19. Here, we report the pilot-scale production of an inactivated SARS-CoV-2 vaccine candidate (BBIBP-CorV) that induces high levels of neutralizing antibodies titers in mice, rats, guinea pigs, rabbits and nonhuman primates (cynomolgus monkeys and rhesus macaques) to provide protection against SARS-CoV-2. Two-dose immunizations using 2 μg/dose of BBIBP-CorV provided highly efficient protection against SARS-CoV-2 intratracheal challenge in rhesus macaques, without detectable antibody-dependent enhancement of infection. In addition, BBIBP-CorV exhibits efficient productivity and good genetic stability for vaccine manufacture. These results support the further evaluation of BBIBP-CorV in a clinical trial.
            Article 0 comments Cited 427 times – based on 0 reviews     Review now
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              Uveitis following the BNT162b2 mRNA vaccination against SARS-CoV-2 infection : a possible association

              Tamar Rabinovitch, Yael Ben-Arie-Weintrob, Tamar Hareuveni-Blum … (2021)
              To describe uveitis cases after the BNT162b2 mRNA SARS-CoV-2 vaccination.
              Article 0 comments Cited 63 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Case Rep Ophthalmol
                Journal ID (iso-abbrev): Case Rep Ophthalmol
                Journal ID (publisher-id): COP
                Title: Case Reports in Ophthalmology
                Publisher: S. Karger AG (Allschwilerstrasse 10, P.O. Box · Postfach · Case postale, CH–4009, Basel, Switzerland · Schweiz · Suisse, Phone: +41 61 306 11 11, Fax: +41 61 306 12 34, karger@karger.com )
                ISSN (Electronic): 1663-2699
                Publication date Collection: Jan-Apr 2022
                Publication date (Electronic): 4 March 2022
                Publication date PMC-release: 4 March 2022
                Volume: 13
                Issue: 1
                Pages: 124-127
                Affiliations
                Department of Ophthalmology, Sanggye Paik Hospital, Inje University of Korea, College of Medicine, Seoul, Republic of Korea
                Author notes
                Article
                Publisher ID: cop-0013-0124
                DOI: 10.1159/000521785
                PMC ID: 8958598
                PubMed ID: 35431883
                SO-VID: 50bacbf3-47cd-4845-8ee8-d3b48c917307
                Copyright © Copyright © 2022 by S. Karger AG, Basel
                License:

                This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.

                History
                Date received : 23 December 2021
                Date accepted : 30 December 2021
                Date: 2022
                Page count
                Figures: 2, References: 13, Pages: 4
                Categories
                Subject: Case Report

                Keywords: covid-19,uveitis,vaccination
                Data availability:
                Keywords: covid-19, uveitis, vaccination

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