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      Inhibition of microRNA-29c protects the brain in a rat model of prolonged hypothermic circulatory arrest.

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          Abstract

          We sought to investigate the cerebroprotection of a novel microRNA mechanism by targeting peroxisome proliferator-activated receptor gamma coactivator 1-alpha in a rat model of prolonged deep hypothermia circulatory arrest.

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          Author and article information

          Journal
          J. Thorac. Cardiovasc. Surg.
          The Journal of thoracic and cardiovascular surgery
          Elsevier BV
          1097-685X
          0022-5223
          Sep 2015
          : 150
          : 3
          Affiliations
          [1 ] Department of Cardiac Surgery, First Affiliated Hospital, China Medical University, Shenyang, China.
          [2 ] Department of Cardiac Surgery, First Affiliated Hospital, China Medical University, Shenyang, China. Electronic address: cmugtx@sina.com.
          Article
          S0022-5223(15)01086-7
          10.1016/j.jtcvs.2015.04.062
          26254749
          511f2a2c-ecbb-44cf-a18f-d845d4dba279
          History

          hypothermic circulatory arrest,microRNA,brain
          hypothermic circulatory arrest, microRNA, brain

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