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      Trilostane treatment of 78 dogs with pituitary-dependent hyperadrenocorticism

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      Veterinary Record
      BMJ

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          Assessment of two tests for the diagnosis of canine hyperadrenocorticism.

          The low-dose dexamethasone suppression test and the urinary corticoid/creatinine ratio were assessed in 166 and 150 dogs, respectively, for their value in the diagnosis of hyperadrenocorticism. The diagnostic accuracy of the low-dose dexamethasone suppression test was 0.83, with a 95 per cent confidence interval from 0.76 to 0.88. The urinary corticoid/creatinine ratio had a diagnostic accuracy of 0.91 with a 95 per cent confidence interval from 0.85 to 0.95. The high predictive value of a negative corticoid/creatinine ratio (0.98; confidence interval 0.80 to 1.00) and the low cost of this test makes it preferable for screening purposes to the low-dose dexamethasone suppression test for which the predictive value of a negative test was calculated as 0.5g (confidence interval 0.43 to 0.73).
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            EXPERIENCE WITH TRILOSTANE IN THE TREATMENT OF CUSHING'S SYNDROME

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              Trilostane in the management of Cushing's syndrome

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                Author and article information

                Journal
                Veterinary Record
                Veterinary Record
                BMJ
                0042-4900
                2042-7670
                June 29 2002
                June 29 2002
                : 150
                : 26
                : 799-804
                Article
                10.1136/vr.150.26.799
                12120922
                517c7ebc-63be-4a52-a23b-762241a37eda
                © 2002
                History

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