The Formosan subterranean termite, Coptotermes formosanus Shiraki, 1909, is a highly destructive structural pest endemic to East Asia. We report a land-based establishment of C. formosanus in Petah Tikva, Israel, over 6000 km from its nearest previous locality in China. The species’ identity was confirmed by soldier morphology and by COI sequence data. In addition, a population discovered in 1992 in suburban San Diego, California, USA, remains viable. Marathon hosts the first infestation of C. formosanus in the Florida Keys. The world distribution of C. formosanus is presented, and the biogeography and mechanisms of spread of this termite are discussed.