Contributors
Moon Soo Park: Role: ConceptualizationRole: Data curationRole: InvestigationRole: ValidationRole:
Writing – original draftRole: Writing – review & editing
Chang-Nam Kang: Role: ConceptualizationRole: Data curationRole: InvestigationRole: Validation
Woo-Suk Lee: Role: ConceptualizationRole: Data curationRole: InvestigationRole: Validation
Ho-Joong Kim: Role: ConceptualizationRole: Data curationRole: InvestigationRole: Validation
Sahnghoon Lee: Role: ConceptualizationRole: Data curationRole: InvestigationRole: Validation
Jin Hwan Kim: Role: ConceptualizationRole: Data curationRole: InvestigationRole: Validation
Sang-Jin Shin: Role: ConceptualizationRole: Data curationRole: InvestigationRole: Validation
Seong-Hwan Moon:
ORCID: http://orcid.org/0000-0002-5165-1159
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: SupervisionRole: Validation
Cristina Vassalle: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
27
January
2020
Publication date Collection: 2020
Volume: 15
Issue: 1
Electronic Location Identifier: e0226184
Affiliations
[1
]
Department of Orthopaedic Surgery, Medical College of Hallym University, Gyeonggi-do,
Republic of Korea
[2
]
Department of Orthopedic Surgery, Hanyang University College of Medicine, Seoul, Republic
of Korea
[3
]
Department of Orthopedic Surgery, Gangnam Severance Hospital, Seoul, Republic of Korea
[4
]
Spine Center and Department of Orthopaedic Surgery, Seoul National University Bundang
Hospital, Seoul National University College of Medicine, Gyeonggi-do, Republic of
Korea
[5
]
Department of Orthopaedic Surgery, Seoul National University, Seoul National University
College of Medicine, Seoul, Republic of Korea
[6
]
Department of Orthopaedic Surgery, Ilsan Paik Hospital, Inje University College of
Medicine, Gyeonggi-do, Republic of Korea
[7
]
Department of Orthopaedic Surgery, Mokdong Hospital, Ewha Womans University College
of Medicine, Seoul, Republic of Korea
[8
]
Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, Republic
of Korea
Fondazione Toscana Gabriele Monasterio, ITALY
Author notes
Competing Interests: This study was supported by a research fund from Hanmi Pharmaceutical Co., Ltd (grant
number HM-IITNAX-001). NAXOZOL(Naproxen, Esomeprazole strontium) was provided by Hanmi
Pharmaceutical Co., Ltd. The funder provided support in the form of salaries for authors
[MSP, CNK, WSL, HJK, SHL, JHK, SJS, SHM]. NAXOZOL is a combination drug of naproxen
and esomeprazole strontium ("esomezol" proved in FDA) as a product marketed in only
Korea currently. NAXOZOL was patented in 2013 as it contains esomeprazole strontium
developed in Hanmi pharmaceutical company. This does not alter our adherence to PLOS
ONE policies on sharing data and materials.
Author information
Article
Publisher ID:
PONE-D-19-04676
DOI: 10.1371/journal.pone.0226184
PMC ID: 6984721
PubMed ID: 31986170
SO-VID: 52217df8-8d06-4092-99c1-fc50b50113b0
Copyright © © 2020 Park et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 20
February
2019
Date
accepted
: 8
October
2019
Page count
Figures: 1,
Tables: 7,
Pages: 14
Funding
Funded by: Hanmi Pharmaceutical Co.,Ltd
Award ID: HM-IIT-NAX-001
Award Recipient
:
ORCID: http://orcid.org/0000-0002-5165-1159
Seong-Hwan Moon
This study was supported by a research fund from Hanmi Pharmaceutical Co., Ltd (grant
number HM-IITNAX-001). NAXOZOL® (Naproxen, Esomeprazole strontium) was provided by
Hanmi Pharmaceutical Co., Ltd. The funder provided support in the form of salaries
for authors [MSP, CNK, WSL, HJK, SHL, JHK, SJS, SHM], but did not have any additional
role in the study design, data collection, and analysis, decision to publish, or preparation
of the manuscript. The funder was not involved in any part of the trial implementation
or data analysis. The specific roles of these authors are articulated in the ‘author
contributions’ section.
Categories
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Rheumatology
Subject:
Arthritis
Subject:
Osteoarthritis
Subject:
Medicine and health sciences
Subject:
Pharmacology
Subject:
Drugs
Subject:
Analgesics
Subject:
NSAIDs
Subject:
Medicine and health sciences
Subject:
Pain management
Subject:
Analgesics
Subject:
NSAIDs
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Elements
Subject:
Strontium
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Digestive System
Subject:
Gastrointestinal Tract
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Digestive System
Subject:
Gastrointestinal Tract
Subject:
Research and Analysis Methods
Subject:
Research Design
Subject:
Clinical Research Design
Subject:
Adverse Events
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Elements
Subject:
Magnesium
Subject:
Medicine and Health Sciences
Subject:
Gastroenterology and Hepatology
Subject:
Gastrointestinal Infections
Subject:
Medicine and Health Sciences
Subject:
Gastroenterology and Hepatology
Subject:
Gastrointestinal Cancers
Custom metadata
