38
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      The ASRG database: identification and survey of Arabidopsis thaliana genes involved in pre-mRNA splicing

      product-review
      1 , 1 , 2 ,
      Genome Biology
      BioMed Central

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The database of Arabidopsis splicing related genes includes classification of genes encoding snRNAs and other splicing related proteins, together with information on gene structure, alternative splicing, gene duplications and phylogenetic relationships.

          Abstract

          A total of 74 small nuclear RNA (snRNA) genes and 395 genes encoding splicing-related proteins were identified in the Arabidopsis genome by sequence comparison and motif searches, including the previously elusive U4atac snRNA gene. Most of the genes have not been studied experimentally. Classification of these genes and detailed information on gene structure, alternative splicing, gene duplications and phylogenetic relationships are made accessible as a comprehensive database of Arabidopsis Splicing Related Genes (ASRG) on our website.

          Related collections

          Most cited references77

          • Record: found
          • Abstract: found
          • Article: not found

          Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.

          The completion of the Arabidopsis thaliana genome sequence allows a comparative analysis of transcriptional regulators across the three eukaryotic kingdoms. Arabidopsis dedicates over 5% of its genome to code for more than 1500 transcription factors, about 45% of which are from families specific to plants. Arabidopsis transcription factors that belong to families common to all eukaryotes do not share significant similarity with those of the other kingdoms beyond the conserved DNA binding domains, many of which have been arranged in combinations specific to each lineage. The genome-wide comparison reveals the evolutionary generation of diversity in the regulation of transcription.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The origins of genomic duplications in Arabidopsis.

            Large segmental duplications cover much of the Arabidopsis thaliana genome. Little is known about their origins. We show that they are primarily due to at least four different large-scale duplication events that occurred 100 to 200 million years ago, a formative period in the diversification of the angiosperms. A better understanding of the complex structural history of angiosperm genomes is necessary to make full use of Arabidopsis as a genetic model for other plant species.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Spliceosomal UsnRNP biogenesis, structure and function.

              Significant advances have been made in elucidating the biogenesis pathway and three-dimensional structure of the UsnRNPs, the building blocks of the spliceosome. U2 and U4/U6*U5 tri-snRNPs functionally associate with the pre-mRNA at an earlier stage of spliceosome assembly than previously thought, and additional evidence supporting UsnRNA-mediated catalysis of pre-mRNA splicing has been presented.
                Bookmark

                Author and article information

                Journal
                Genome Biol
                Genome Biology
                BioMed Central (London )
                1465-6906
                1465-6914
                2004
                29 November 2004
                : 5
                : 12
                : R102
                Affiliations
                [1 ]Department of Genetics, Development and Cell Biology Iowa State University, Ames, IA 50011-3260, USA
                [2 ]Department of Statistics, Iowa State University, Ames, IA 50011-3260, USA
                Article
                gb-2004-5-12-r102
                10.1186/gb-2004-5-12-r102
                545797
                15575968
                5243c7ed-5cc7-463d-8e6b-2063ecb5ebfd
                Copyright © 2004 Wang and Brendel; licensee BioMed Central Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 25 June 2004
                : 6 September 2004
                : 20 October 2004
                Categories
                Software

                Genetics
                Genetics

                Comments

                Comment on this article