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      Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents.

      1 ,
      Chemical Society reviews
      Royal Society of Chemistry (RSC)

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          Abstract

          Various magnetic nanoparticles have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents owing to their unique characteristics, including efficient contrast effects, biocompatibility, and versatile surface functionalization capability. Nanoparticles with high relaxivity are very desirable because they would increase the accuracy of MRI. Recent progress in nanotechnology enables fine control of the size, crystal structure, and surface properties of iron oxide nanoparticles. In this tutorial review, we discuss how MRI contrast effects can be improved by controlling the size, composition, doping, assembly, and surface properties of iron-oxide-based nanoparticles.

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          Author and article information

          Journal
          Chem Soc Rev
          Chemical Society reviews
          Royal Society of Chemistry (RSC)
          1460-4744
          0306-0012
          Apr 07 2012
          : 41
          : 7
          Affiliations
          [1 ] World Class University Program of Chemical Convergence for Energy & Environment, and School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-744, Korea.
          Article
          10.1039/c1cs15248c
          22138852
          528480e3-0475-4368-bd1a-adb49e784ee5
          History

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