0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Challenges related to development of bioabsorbable vascular stents.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Vascular stents have revolutionised the field of interventional cardiology. Once an artery has healed, however, stents are no longer thought to serve a functional role. Bioabsorbable stents would be preferred to permanent implants if they maintain arterial architecture, minimise device/host interactions, and reduce the need for long-term anticoagulation therapy. Technical challenges to develop and commercialise a successful bioabsorbable stent relate to identification of materials and stent designs capable of balancing acute and chronic mechanical properties, degradation time, and biocompatibility. Successful programs will be ones that achieve these requirements with uncompromised product deliverability, efficacy and safety. Many materials currently proposed for use in bioabsorbable stents take longer than 24 months to degrade and so may not meet these criteria. We describe here the Medtronic CardioVascular bioabsorbable program which focuses on developing a degradable stent for superficial femoral arteries that targets degradation in less than 12 months.

          Related collections

          Author and article information

          Journal
          EuroIntervention
          EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
          Europa Digital & Publishing
          1969-6213
          1774-024X
          Dec 15 2009
          : 5 Suppl F
          Affiliations
          [1 ] Science & Technology, Medtronic CardioVascular, 3576 Unocal Place, Santa Rosa, CA 95403, USA.
          Article
          EIJV5IFA12
          10.4244/EIJV5IFA12
          22100681
          52973309-00a8-478b-ac67-18a0a4cf2153
          History

          Comments

          Comment on this article