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      Researches advances on the mechanism of the effect of adverse childhood experiences on allostatic load

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          Abstract

          Allostatic load (AL) is related to stress. Adverse childhood experiences (ACEs), as a common stress in childhood, can make a serious and lasting impact on it. Allostatic load can reflect the wear and tear of an individual’s physiological system. This article mainly reviews the functional changes of several systems of AL who have experienced ACEs, including neuroendocrine, metabolism, immune, and cardiovascular systems, as well as the different effects of the occurrence time and subtypes of ACES on AL, providing some theoretical basis for the development of early intervention plans in the future and reducing the occurrence and development of deleterious outcomes.

          Abstract

          【摘要】非稳态负荷 (allostatic load, AL) 主要与压力应激有关, 而童年期逆境 (adverse childhood experiences, ACEs) 作为 童年时期常见的应激源能对其产生严重且持久的影响。AL能够反映个体多个生理系统的综合磨损情况。该文主要综述 了经历ACEs的个体对其AL各系统的影响和作用机制, 以及ACEs的发生时间、亚型对AL的不同影响, 为未来制定早期 干预计划, 减少不良结局的发生发展提供一定的理论基础。

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          Author and article information

          Journal
          CJSH
          Chinese Journal of School Health
          Chinese Journal of School Health (China )
          1000-9817
          01 March 2022
          01 April 2022
          : 43
          : 3
          : 472-475
          Affiliations
          [1] 1Department of Nursing, Harbin Medical University, Harbin (150081), China
          Author notes
          *Corresponding author: ZHANG Hui, E-mail: zhanghui801123@ 123456163.com
          Article
          j.cnki.1000-9817.2022.03.037
          10.16835/j.cnki.1000-9817.2022.03.037
          52aae62e-d86b-4653-aef8-900fd06dcb0f
          © 2022 Chinese Journal of School Health

          This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

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          Self URI (journal-page): http://www.cjsh.org.cn
          Categories
          Journal Article

          Ophthalmology & Optometry,Pediatrics,Nutrition & Dietetics,Clinical Psychology & Psychiatry,Public health
          Mental health,Behavior and behavior mechanisms,Life change events

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