10
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Barrett's esophagus: Age, prevalence, and extent of columnar epithelium

      ,
      Gastroenterology
      Elsevier BV

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The development of Barrett's esophagus was studied using data from 51,311 patients undergoing upper gastrointestinal endoscopy between 1976 and 1989. Three hundred seventy-seven patients had greater than or equal to 3-cm columnar epithelium in the esophagus and no carcinoma. The prevalence of Barrett's esophagus increased with age to reach a plateau by the seventh decade. Half of the maximum prevalence was reached by age 40 years, the estimated median age of development of the disorder. Unlike prevalence, the mean length of columnar epithelium did not increase with age. No significant change in length was found in 21 patients followed up for a mean of 7.3 years (mean initial length, 8.29 +/- 0.85 cm; mean final length, 8.33 +/- 0.77 cm). The length of columnar epithelium did not increase in the presence of esophagitis or decrease when esophagitis was absent. Mean age at diagnosis of Barrett's esophagus was 63 years without carcinoma and 64 years in a separate group of patients with adenocarcinoma. The data are consistent with a fairly rapid evolution of Barrett's esophagus to its full length with little subsequent change. Barrett's esophagus may develop more than 20 years before the mean age of clinical recognition or the development of esophageal adenocarcinoma.

          Related collections

          Most cited references15

          • Record: found
          • Abstract: found
          • Article: not found

          The incidence of adenocarcinoma in columnar-lined (Barrett's) esophagus.

          We evaluated the risk of adenocarcinoma developing in Barrett's esophagus (esophagus lined with columnar epithelium). Mayo Clinic records were reviewed, and all cases that met predefined histologic criteria for the diagnosis of Barrett's esophagus in 1979 or earlier were included. In 18 of 122 such cases, adenocarcinoma of the esophagus and Barrett's esophagus were diagnosed simultaneously. The status of the remaining 104 cases was determined after a mean interval of 8.5 years. During this time, adenocarcinoma of the esophagus developed in 2 patients, and 24 died from other causes. We conclude that although the incidence of esophageal adenocarcinoma is increased in patients with symptomatic Barrett's esophagus, it does not occur in the majority of such patients.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Chronic peptic ulcerz of the œophagus and ‘œsophagitis’

              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Barrett's esophagus

                Bookmark

                Author and article information

                Journal
                Gastroenterology
                Gastroenterology
                Elsevier BV
                00165085
                October 1992
                October 1992
                : 103
                : 4
                : 1241-1245
                Article
                10.1016/0016-5085(92)91510-B
                1397881
                532caa8c-e772-451a-88db-d653158a97ae
                © 1992

                https://www.elsevier.com/tdm/userlicense/1.0/

                History

                Comments

                Comment on this article