Selective Afterload Reduction in the Treatment of Septal Rupture Complicating Myocardial Infarction

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Interventricular septal rupture complicating acute myocardial infarction is usually fatal unless corrective surgery can be delayed until adequate healing of the septum has occurred. A case is reported in which the degree of shunting through the ventricular septal defect was reduced by the use of hydralazine, a drug which selectively reduces peripheral vascular resistance. In spite of the fact that this patient eventually died before surgical repair could be carried out, the hydralazine did bring about a significant improvement in the left-to-right shunt ratio.

Related collections

Author and article information

Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1980

Publication date (Print): 1980

Publication date (Electronic): 31 October 2008

Volume: 65

Issue: 1

Pages: 59-64

Affiliations

Cardiac Care Unit, Division of Cardiology, Medical Service, St. Luke’s Hospital Center, New York, N.Y

Article

Publisher ID: 170795 Other ID: Cardiology 1980;65:59–64

DOI: 10.1159/000170795

PubMed ID: 7363281

SO-VID: 53307a2b-d14e-4a8d-a583-90a27c2bd96c

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

Call for Papers: Novel Methods in Vascular and Lymphatic Physiology

Submit here by June 30, 2025

Selective Afterload Reduction in the Treatment of Septal Rupture Complicating Myocardial Infarction

Read this article at

Abstract

Related collections

Karger: Cardiovascular System

Author and article information

Journal

Affiliations

Article

History

Page count

Categories

Comments

Comment on this article

Similar content 60

Cited by 1