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      Short-Term Growth Hormone Therapy Increases Serum Lipoprotein (a) Levels in Normal Short Children without Growth Hormone Deficiency

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          We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 ± 5, 161.6 ± 14.7 and 152.5 ± 18.5%(mean ± SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

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          Hormone Research in Paediatrics
          S. Karger AG
          09 December 2008
          : 46
          : 1
          : 38-40
          aPediatric Diagnostic and Therapeutic Center and bClinical Biochemistry Laboratories, Soroka Medical University Center, Beer-Sheva, Israel
          184975 Horm Res 1996;46:38–40
          © 1996 S. Karger AG, Basel

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