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      Elevated Pituitary LH and Depressed Pituitary Prolactin Levels in Female Hamsters with Pineal-Induced Gonadal Atrophy and the Effects of Chronic Treatment with Synthetic LRF

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          Abstract

          Light deprivation by blinding leads to involution of the reproductive organs and cessation of cyclic vaginal phenomena in adult fe-male hamsters. Associated with the atrophy of the reproductive system are elevated LH levels and depressed prolactin levels in the anterior pituitary gland. Chronic treatment (15 or 30 days) of blind hamsters with synthetic luteinizing hormone releasing factor (LRF) decreased pituitary levels and elevated plasma titers of LH. Neither pituitary nor plasma levels of prolactin were influenced by LRF treatment. Pinealectomy completely reversed the effects of blinding on the reproductive organs and on the pituitary levels of LH and prolactin.

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          Author and article information

          Journal
          NEN
          Neuroendocrinology
          10.1159/issn.0028-3835
          Neuroendocrinology
          S. Karger AG
          0028-3835
          1423-0194
          1974
          1974
          20 March 2008
          : 14
          : 5
          : 310-320
          Affiliations
          Department of Anatomy, The University of Texas Health Science Center at San Antonio, San Antonio, Tex.
          Article
          122274 Neuroendocrinology 1974;14:310–320
          10.1159/000122274
          4603274
          © 1974 S. Karger AG, Basel

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          Page count
          Pages: 11
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