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Biodegradable and electrically conducting polymers for biomedical applications

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Progress in Polymer Science

Elsevier BV

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      Tissue engineering

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        Scaffolds in tissue engineering bone and cartilage.

        Musculoskeletal tissue, bone and cartilage are under extensive investigation in tissue engineering research. A number of biodegradable and bioresorbable materials, as well as scaffold designs, have been experimentally and/or clinically studied. Ideally, a scaffold should have the following characteristics: (i) three-dimensional and highly porous with an interconnected pore network for cell growth and flow transport of nutrients and metabolic waste; (ii) biocompatible and bioresorbable with a controllable degradation and resorption rate to match cell/tissue growth in vitro and/or in vivo; (iii) suitable surface chemistry for cell attachment, proliferation, and differentiation and (iv) mechanical properties to match those of the tissues at the site of implantation. This paper reviews research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view.
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          Hydrogels for tissue engineering.

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            Author and article information

            Journal
            Progress in Polymer Science
            Progress in Polymer Science
            Elsevier BV
            00796700
            September 2013
            September 2013
            : 38
            : 9
            : 1263-1286
            10.1016/j.progpolymsci.2013.06.003
            © 2013

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