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      Differential Utility of Antiarrhythmic Agents

      Cardiology

      S. Karger AG

      Ventricular arrhythmias, Sudden death, Antiarrhythmic agents

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          Abstract

          Sudden cardiac death (SCD), which is recognized as the most common cause of death in adults, in 80% of cases results from a ventricular tachyarrhythmia that subsequently degenerates into ventricular fibrillation. Ventricular arrhythmias have been identified as a major factor in predicting a high risk of SCD and can be classified as benign, potentially lethal, or lethal. This system is based on the likelihood that the rhythm type predicts the occurrence of sudden death. Antiarrhythmic agents are employed to eliminate ventricular arrhythmias and their sequelae, particularly hemodynamic consequences. Many physicians use these drugs with the additional hope of preventing sudden death, although to date no data support such use. This article details the comparative utility of commonly available antiarrhythmic agents in terms of their safety and efficacy, and defines the bases for the recommendations of an algorithm that can be used to choose among the various drugs.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          978-3-8055-4629-4
          978-3-318-01764-9
          0008-6312
          1421-9751
          1987
          1987
          11 November 2008
          : 74
          : Suppl 2
          : 57-66
          Affiliations
          Likoff Cardiovascular Institute, Hahnemann University Hospital, Philadelphia, Pa., USA
          Article
          174287 Cardiology 1987;74:57–66
          10.1159/000174287
          3621279
          © 1987 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 10
          Categories
          Paper

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