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      Estimating time-varying networks

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          Abstract

          Stochastic networks are a plausible representation of the relational information among entities in dynamic systems such as living cells or social communities. While there is a rich literature in estimating a static or temporally invariant network from observation data, little has been done toward estimating time-varying networks from time series of entity attributes. In this paper we present two new machine learning methods for estimating time-varying networks, which both build on a temporally smoothed \(l_1\)-regularized logistic regression formalism that can be cast as a standard convex-optimization problem and solved efficiently using generic solvers scalable to large networks. We report promising results on recovering simulated time-varying networks. For real data sets, we reverse engineer the latent sequence of temporally rewiring political networks between Senators from the US Senate voting records and the latent evolving regulatory networks underlying 588 genes across the life cycle of Drosophila melanogaster from the microarray time course.

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          Most cited references17

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          Variable Selection via Nonconcave Penalized Likelihood and its Oracle Properties

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            Sparsity and smoothness via the fused lasso

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              Discussion of "Least angle regression" by Efron et al

              (2004)
              Discussion of ``Least angle regression'' by Efron et al. [math.ST/0406456]
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                Author and article information

                Journal
                2008-12-30
                2010-10-20
                Article
                10.1214/09-AOAS308
                0812.5087
                54d9f15f-ca88-456a-9986-0c49ffff038e

                http://arxiv.org/licenses/nonexclusive-distrib/1.0/

                History
                Custom metadata
                IMS-AOAS-AOAS308
                Annals of Applied Statistics 2010, Vol. 4, No. 1, 94-123
                Published in at http://dx.doi.org/10.1214/09-AOAS308 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
                stat.ML q-bio.MN q-bio.QM stat.AP stat.ME
                vtex

                Applications,Quantitative & Systems biology,Molecular biology,Machine learning,Methodology

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