5
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Thymic carcinoma: update of current diagnostic criteria and histologic types.

      Seminars in diagnostic pathology
      Biological Markers, analysis, Humans, Immunohistochemistry, Thymoma, diagnosis, Thymus Neoplasms

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Thymic carcinomas are rare tumors thought to derive from thymic epithelium. Because of the complex embryological origin of the thymus, whose development includes contributions from the third and, to a lesser extent, the fourth pharyngeal pouches, thymic carcinomas are endowed with great morphologic heterogeneity. A large number of histologic types have been described that resemble tumors arising in other organs. Unfortunately, no definitive pathognomonic histological features or immunohistochemical markers are associated with these tumors, making them a real challenge for diagnosis. Because of their close similarity with tumors arising at other organs, the diagnosis of thymic carcinoma must be regarded, for the most part, as a diagnosis of exclusion. This review will focus on current criteria for diagnosis of these tumors, with a review of the various histopathologic appearances that they can adopt.

          Related collections

          Author and article information

          Journal
          16711401
          10.1053/j.semdp.2006.02.006

          Chemistry
          Biological Markers,analysis,Humans,Immunohistochemistry,Thymoma,diagnosis,Thymus Neoplasms
          Chemistry
          Biological Markers, analysis, Humans, Immunohistochemistry, Thymoma, diagnosis, Thymus Neoplasms

          Comments

          Comment on this article