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Effect of dietary turmeric (curcuma longa) on iron-induced lipid peroxidation in the rat liver
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Abstract
Male Wistar rats were fed a control diet or the control diet supplemented with 1%
(by weight) turmeric for 10 wk. In rats injected with 30 mg Fe2+/kg body weight, lipid
peroxidation was 29 and 35% lower in liver homogenates and microsomes, respectively,
of turmeric-fed rats than in those of rats fed the control diet. The activities of
superoxide dismutase, catalase and glutathione peroxidase were higher (by 19, 19 and
20%, respectively) in liver homogenates of rats fed the turmeric-containing diet in
comparison with the controls. These studies indicate that dietary turmeric lowers
lipid peroxidation by enhancing the activities of antioxidant enzymes.