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      Validation of the Identification and Intervention for Dementia in Elderly Africans (IDEA) cognitive screen in Nigeria and Tanzania

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          Abstract

          Background

          We have previously described the development of the Identification and Intervention for Dementia in Elderly Africans (IDEA) cognitive screen for use in populations with low levels of formal education. The IDEA cognitive screen was developed and field-tested in an elderly, community-based population in rural Tanzania with a relatively high prevalence of cognitive impairment. The aim of this study was to validate the IDEA cognitive screen as an assessment of major cognitive impairment in hospital settings in Nigeria and Tanzania.

          Methods

          In Nigeria, 121 consecutive elderly medical clinic outpatients reviewed at the University College Hospital, Ibadan were screened using the IDEA cognitive screen. In Tanzania, 97 consecutive inpatients admitted to Mawenzi Regional Hospital (MRH), Moshi, and 108 consecutive medical clinic outpatients attending the geriatric medicine clinic at MRH were screened. Inter-rater reliability was assessed in Tanzanian outpatients attending St Joseph’s Hospital in Moshi using three raters. A diagnosis of dementia or delirium (DSM-IV criteria) was classified as major cognitive impairment and was provided independently by a physician blinded to the results of the screening assessment.

          Results

          The area under the receiver operating characteristic (AUROC) curve in Nigerian outpatients, Tanzanian outpatients and Tanzanian inpatients was 0.990, 0.919 and 0.917 respectively. Inter-rater reliability was good (intra-class correlation coefficient 0.742 to 0.791). In regression models, the cognitive screen did not appear to be educationally biased.

          Conclusions

          The IDEA cognitive screen performed well in these populations and should prove useful in screening for dementia and delirium in other areas of sub-Saharan Africa.

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          Most cited references20

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          Diagnostic and statistical manual of mental disorders.

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            Delirium in elderly adults: diagnosis, prevention and treatment.

            Delirium is a common and serious acute neuropsychiatric syndrome with core features of inattention and global cognitive dysfunction. The etiologies of delirium are diverse and multifactorial and often reflect the pathophysiological consequences of an acute medical illness, medical complication or drug intoxication. Delirium can have a widely variable presentation, and is often missed and underdiagnosed as a result. At present, the diagnosis of delirium is clinically based and depends on the presence or absence of certain features. Management strategies for delirium are focused on prevention and symptom management. This article reviews current clinical practice in delirium in elderly individuals, including the diagnosis, treatment, outcomes and economic impact of this syndrome. Areas of future research are also discussed.
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              The GPCOG: a new screening test for dementia designed for general practice.

              To design and test a brief, efficient dementia-screening instrument for use by general practitioners (GPs). The General Practitioner Assessment of Cognition (GPCOG) consists of cognitive test items and historical questions asked of an informant. The validity of the measure was assessed by comparison with the criterion standard of diagnoses of dementia derived from the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition). Primary care doctors' offices. Sixty-seven GPs administered the GPCOG to 283 community-dwelling patients aged 50 to 74 with memory complaints or aged 75 and older. The Cambridge Mental Disorder of the Elderly Examination, the Abbreviated Mental Test (AMT), the Mini-Mental State Examination (MMSE), the 15-item Geriatric Depression Scale, and the 12-item Short-Form Health Survey. The GPCOG was reliable and superior to the AMT (and possibly to the MMSE) in detecting dementia. The two-stage method of administering the GPCOG (cognitive testing followed by informant questions if necessary)had a sensitivity of 0.85, a specificity of 0.86, a misclassification rate of 14%, and positive predictive value of 71.4%. Patient interviews took less than 4 minutes to administer and informant interviews less than 2 minutes. The instrument was reported by GPs to be practical to administer and was acceptable to patients. The GPCOG is a valid, efficient, well-accepted instrument for dementia screening in primary care.
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                Author and article information

                Contributors
                stella-maria.paddick@ncl.ac.uk
                wagray70@gmail.com
                LOgunjimi@yahoo.com
                Bingileki.lwezuala@gmail.com
                lyde18@yahoo.com
                kisolialoyce@yahoo.com
                KissimaJ10@yahoo.co.uk
                godfreymbowe81@yahoo.com
                sarah.mkenda@yahoo.co.uk
                Catherine.dotchin@nhct.nhs.uk
                richard.walker@nhct.nhs.uk
                mushideclare65@gmail.com
                cecilia.collingwood@newcastle.ac.uk
                aogunniyi53@yahoo.com
                Journal
                BMC Geriatr
                BMC Geriatr
                BMC Geriatrics
                BioMed Central (London )
                1471-2318
                25 April 2015
                25 April 2015
                2015
                : 15
                : 53
                Affiliations
                [ ]Northumbria Healthcare NHS Foundation Trust, North Tyneside General Hospital, North Shields, UK
                [ ]Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
                [ ]University College Hospital, University of Ibadan, Ibadan, Nigeria
                [ ]Mawenzi Regional Hospital, Moshi, Tanzania
                [ ]Hai District Hospital, Boman’gombe, Kilimanjaro Tanzania
                [ ]Kilimanjaro Christian Medical University College, Moshi, Tanzania
                [ ]Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK
                [ ]Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
                [ ]The Medical School, Newcastle University, Newcastle upon Tyne, UK
                Article
                40
                10.1186/s12877-015-0040-1
                4455989
                25908439
                5523c829-bc48-42ef-b35e-cfd8e5a4d8ab
                © Paddick et al. 2015

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 23 October 2014
                : 25 March 2015
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2015

                Geriatric medicine
                dementia,delirium,screening,nigeria,tanzania,africa,validation
                Geriatric medicine
                dementia, delirium, screening, nigeria, tanzania, africa, validation

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