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      Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications

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      Drug Discovery Today
      Elsevier BV

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          Abstract

          Poly(amidoamine) (PAMAM) dendrimers are the first complete dendrimer family to be synthesized, characterized and commercialized. Based on this extensive activity, they are recognized as a unique new class of synthetic nanostructures. Dendrimers allow the precise control of size, shape and placement of functional groups that is desirable for many life science applications. From this perspective, this review focuses on crucial properties of biomimetic dendrimers that will broaden the potential for their use as macromolecular vectors in novel drug delivery and biomedical applications.

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          Author and article information

          Journal
          Drug Discovery Today
          Drug Discovery Today
          Elsevier BV
          13596446
          April 2001
          April 2001
          : 6
          : 8
          : 427-436
          Article
          10.1016/S1359-6446(01)01757-3
          11301287
          557710be-072e-47b4-a59d-be6280770fa3
          © 2001

          https://www.elsevier.com/tdm/userlicense/1.0/

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