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      Neoplasia after Successful Renal Transplantation

      , , ,

      Nephron

      S. Karger AG

      Analgesic nephropathy, Renal transplantation, Neoplasia

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          Abstract

          Neoplasia developed in 14 of the first 193 patients to receive renal transplants at the Johannesburg Hospital. No case of reticulum cell sarcoma was diagnosed and an extremely high incidence of squamous carcinoma of the skin occurred. Of the latter patients, 62.5% originally suffered from analgesic nephropathy, suggesting a possible relationship between the two conditions. Transplant recipients who later developed tumours were less likely to experience rejection episodes than other recipients, and this may suggest a generally depressed immune surveillance system in these particular patients.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1981
          1981
          03 December 2008
          : 29
          : 3-4
          : 119-123
          Affiliations
          Transplant Unit, Department of Medicine and Surgery, Johannesburg Hospital and University of the Witwatersrand, Johannesburg, South Africa
          Article
          182327 Nephron 1981;29:119–123
          10.1159/000182327
          7035982
          © 1981 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 5
          Categories
          Original Paper

          Cardiovascular Medicine, Nephrology

          Analgesic nephropathy, Neoplasia, Renal transplantation

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