Giacomo Gastaldi: Role: ConceptualizationRole: Data curationRole: InvestigationRole: MethodologyRole:
VisualizationRole: Writing – review & editing
Diana Gomes: Role: Data curationRole: Formal analysisRole: InvestigationRole: VisualizationRole:
Writing – original draft
Philippe Schneiter: Role: MethodologyRole: ResourcesRole: ValidationRole: Writing – review & editing
Xavier Montet: Role: Data curationRole: ResourcesRole: Writing – review & editing
Luc Tappy: Role: MethodologyRole: ResourcesRole: ValidationRole: Writing – review & editing
Sophie Clément: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
Project administrationRole: ValidationRole: Writing – original draft
Francesco Negro:
ORCID: http://orcid.org/0000-0003-4046-4806
Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
ResourcesRole: SupervisionRole: Writing – original draft
Jee-Fu Huang: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
6
June
2019
Publication date Collection: 2019
Volume: 14
Issue: 6
Electronic Location Identifier: e0217751
Affiliations
[1
]
Division of Endocrinology, diabetology, hypertension and nutrition, Geneva University
Hospitals, Geneva, Switzerland
[2
]
Department of Pathology and immunology, University of Geneva, Geneva, Switzerland
[3
]
Department of Physiology, Faculty of Biology and Medicine, University of Lausanne,
Lausanne, Switzerland
[4
]
Division of Radiology, Geneva University Hospitals, Geneva, Switzerland
[5
]
Division of Clinical Pathology, Geneva University Hospitals, Geneva, Switzerland
[6
]
Division of Gastroenterology and hepatology, Geneva University Hospitals, Geneva,
Switzerland
Kaohsiung Medical University, TAIWAN
Author notes
Competing Interests: F.N. has received research grants from Gilead and AbbVie, and is advising Gilead,
AbbVie and Merck. This does not alter our adherence to PLoS One policies on sharing
data and materials.
Author information
Article
Publisher ID:
PONE-D-19-05928
DOI: 10.1371/journal.pone.0217751
PMC ID: 6553748
PubMed ID: 31170218
SO-VID: 55a6f148-0de6-40ee-a17f-a0fe9518e702
Copyright © © 2019 Gastaldi et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100001711, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung;
Award ID: 314730-166609
Award Recipient
:
ORCID: http://orcid.org/0000-0003-4046-4806
Francesco Negro
Funded by: Fondation pour la Recherche sur le Diabète
Award Recipient
:
ORCID: http://orcid.org/0000-0003-4046-4806
Francesco Negro
Funded by: funder-id http://dx.doi.org/10.13039/100005564, Gilead Sciences;
Award Recipient
:
ORCID: http://orcid.org/0000-0003-4046-4806
Francesco Negro
This work was supported by: (FN) Gilead Sciences, Inc. Foster City, CA, US,
https://www.gilead.com/; Swiss National Science Foundation (314730-166609 to F.N.),
http://www.snf.ch/en/Pages/default.aspx; FLAGS Foundation and the Fondation pour la Recherche sur le Diabète, Geneva, Switzerland,
http://www.fondation-diabete.ch/. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Diabetic Endocrinology
Subject:
Insulin
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Hormones
Subject:
Insulin
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
RNA viruses
Subject:
Flaviviruses
Subject:
Hepacivirus
Subject:
Hepatitis C virus
Subject:
Biology and life sciences
Subject:
Microbiology
Subject:
Medical microbiology
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Flaviviruses
Subject:
Hepacivirus
Subject:
Hepatitis C virus
Subject:
Medicine and health sciences
Subject:
Pathology and laboratory medicine
Subject:
Pathogens
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Flaviviruses
Subject:
Hepacivirus
Subject:
Hepatitis C virus
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral pathogens
Subject:
Flaviviruses
Subject:
Hepacivirus
Subject:
Hepatitis C virus
Subject:
Biology and life sciences
Subject:
Microbiology
Subject:
Medical microbiology
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Hepatitis viruses
Subject:
Hepatitis C virus
Subject:
Medicine and health sciences
Subject:
Pathology and laboratory medicine
Subject:
Pathogens
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Hepatitis viruses
Subject:
Hepatitis C virus
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral pathogens
Subject:
Hepatitis viruses
Subject:
Hepatitis C virus
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Metabolism
Subject:
Carbohydrate Metabolism
Subject:
Glucose Metabolism
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Organic Compounds
Subject:
Carbohydrates
Subject:
Monosaccharides
Subject:
Glucose
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Organic Chemistry
Subject:
Organic Compounds
Subject:
Carbohydrates
Subject:
Monosaccharides
Subject:
Glucose
Subject:
Medicine and Health Sciences
Subject:
Gastroenterology and Hepatology
Subject:
Liver Diseases
Subject:
Chronic Liver Disease
Subject:
Chronic Hepatitis
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Drugs
Subject:
Antimicrobials
Subject:
Antivirals
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Microbial Control
Subject:
Antimicrobials
Subject:
Antivirals
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Virology
Subject:
Antivirals
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Endocrine Disorders
Subject:
Diabetes Mellitus
Subject:
Type 2 Diabetes
Subject:
Medicine and Health Sciences
Subject:
Metabolic Disorders
Subject:
Diabetes Mellitus
Subject:
Type 2 Diabetes
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Adipose Tissue
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Adipose Tissue
