9
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Evidence for the presence of ‘Ouabain like’ compound in human cerebrospinal fluid

      , , , , , , ,
      Brain Research
      Elsevier BV

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Material extracted and partially purified from human cerebrospinal fluid (CSF) is capable of: a, inhibiting [3H]ouabain binding to rat brain synaptosomes; b, inhibiting the activity of purified pig kidney Na+,K+-ATPase; and c, inhibiting ouabain sensitive induced 86Rb influx to tissue cultured fibroblasts. These results demonstrate the existence of an 'ouabain like' compound (OLC) in human CSF, and are consistent with the hypothesis of the function of this compound as a neuromodulator.

          Related collections

          Author and article information

          Journal
          Brain Research
          Brain Research
          Elsevier BV
          00068993
          January 1985
          January 1985
          : 325
          : 1-2
          : 13-19
          Article
          10.1016/0006-8993(85)90297-5
          2858247
          55b53a71-43e1-4977-94c7-649e60cc0813
          © 1985

          https://www.elsevier.com/tdm/userlicense/1.0/

          History

          Comments

          Comment on this article