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      Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989-1999.

      Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

      Adult, Candida, isolation & purification, Candidiasis, epidemiology, microbiology, Cross Infection, Female, Humans, Intensive Care Units, Male, Middle Aged, United States

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          Abstract

          We describe the annual incidence of primary bloodstream infection (BSI) associated with Candida albicans and common non-albicans species of Candida among patients in intensive care units that participated in the National Nosocomial Infections Surveillance system from 1 January 1989 through 31 December 1999. During the study period, there was a significant decrease in the incidence of C. albicans BSI (P<.001) and a significant increase in the incidence of Candida glabrata BSI (P=.05).

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          Journal
          12173140
          10.1086/342300

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