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      EDUCATIONAL SERIES IN CONGENITAL HEART DISEASE: Echocardiographic assessment of transposition of the great arteries and congenitally corrected transposition of the great arteries

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          Abstract

          Echocardiographic assessment of patients with transposition of the great arteries and congenitally corrected transposition requires awareness of the morphology and commonly associated lesions. The pre-operative echocardiography should include a full segmental and sequential analysis. Post-operative assessment is not possible without awareness of the type of surgical procedure performed and consists of assessing surgical connections and residual lesions.

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          Most cited references28

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          Surgical correction of transposition of the great vessels.

          A Senning (1959)
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            Results of the arterial switch operation in neonates with transposed great arteries.

            The arterial switch operation is judged the best palliative operation for neonates with transposed great arteries. We aimed to assess the value of analysing a large series of unselected cases by this technically demanding operation and formulate a realistic prognosis. We reviewed all 432 neonates (mean age at operation 7 days, mean weight 3.25 kg) who underwent an arterial switch operation between 1987 and 1999. Follow-up (mean time: 4.9 years) was complete in 412 patients. Survival probability and freedom from reoperation was 94% and 78% at 10 years, respectively. 26 patients died, 16 because of myocardial ischaemia. Risk factors for death included early experience, low weight, associated cardiovascular malformations (especially hypoplasia of the right ventricle or aortic arch), and difficult patterns of coronary arteries. The risk of the coronary artery pattern was greatly reduced in those who had recent operations. At last follow-up, 90% of patients had normal life without treatment, and 94% a normal heart function on echocardiography. The arterial switch operation in neonates achieves excellent results mid-term. Obstruction of the translocated coronary arteries is responsible for most deaths and a substantial number of reoperations. Although confirmation is needed, these results allow anticipation of a favourable long-term prognosis.
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              Successful anatomic correction of transposition of the great vessels. A preliminary report.

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                Author and article information

                Journal
                Echo Res Pract
                Echo Res Pract
                echo
                Echo Research and Practice
                Bioscientifica Ltd (Bristol )
                2055-0464
                December 2019
                23 October 2019
                : 6
                : 4
                : R107-R119
                Affiliations
                [1 ]Division of Cardiology , The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
                [2 ]Division of Cardiology , The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
                Author notes
                Correspondence should be addressed to L L Mertens: luc.mertens@ 123456sickkids.ca
                Article
                ERP-19-0047
                10.1530/ERP-19-0047
                6865365
                31729212
                55ed098b-20b1-4a97-950b-bd713c4bed35
                © 2019 The authors

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 13 October 2019
                : 23 October 2019
                Categories
                Review

                congenital heart defects,congenitally corrected transposition of great arteries,transposition of the great arteries

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