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      Sea buckthorn seed oil protects against the oxidative stress produced by thermally oxidized lipids.

      1 , 2

      Food chemistry

      Elsevier BV

      Liver, Oxidative stress, Oxidized vegetable ghee, Rabbits, Sea buckthorn oil, Serum lipids

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          Abstract

          Thermally oxidized vegetable ghee was fed to the rabbits for 14 days with specific doses of sea buckthorn seed oil (SO). The ghee and SO were characterized for quality parameters and fatty acid composition using GC-MS. Rabbits serum lipid profile, hematology and histology were investigated. Major fatty acids were palmitic acid (44%) and oleic acid (46%) in ghee, while SO contains oleic acid (56.4%) and linoleic acid (18.7%). Results showed that oxidized vegetable ghee increases the serum total cholesterol, LDL-cholesterols, triglycerides and decrease the serum glucose. Oxidized ghee produced toxic effects in the liver and hematological parameters. Sea buckthorn oil supplementation significantly lowered the serum LDL-cholesterols, triglycerides and increased serum glucose and body weight of the animals. Sea buckthorn oil was found to reduce the toxic effects and degenerative changes in the liver and thus provides protection against the thermally oxidized lipids induced oxidative stress.

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          Author and article information

          Journal
          Food Chem
          Food chemistry
          Elsevier BV
          0308-8146
          0308-8146
          Nov 01 2015
          : 186
          Affiliations
          [1 ] Department of Biotechnology, University of Malakand, Chakdara, Pakistan. Electronic address: Alamzeb01@yahoo.com.
          [2 ] Department of Biotechnology, University of Malakand, Chakdara, Pakistan.
          Article
          S0308-8146(15)00416-1
          10.1016/j.foodchem.2015.03.053
          25976784

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