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      New Surgical Approach and Rehabilitation After Cemented Total Ankle Arthroplasty

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          Abstract

          Background: According to the conventional postoperative procedure after total ankle arthroplasty (TAA) for end-stage osteoarthritis (OA) and rheumatoid arthritis (RA), mobilization and weight-bearing are currently started after completion of wound healing. Recently, an early rehabilitation program after cemented TAA with a modified anterolateral approach has been attempted because this approach could provide stable wound healing. To investigate the possibility of expediting rehabilitation, this study evaluated the feasibility, safety, and universality of an early rehabilitation program after cemented TAA using a modified anterolateral approach, even when a surgeon was completely changed.

          Methods: This retrospective, observational study investigated 13 consecutive ankles (OA: 11 ankles, RA: two ankles) that had undergone cemented TAA with a modified anterolateral approach. As an early rehabilitation program, after early dorsiflexion mobilization (day three), full weight-bearing/gait exercise was started seven days after surgery (10 days after if malleolar osteotomy was added). Postoperative wound complications were observed and recorded. The number of days of hospitalization was also evaluated. Range of motion (ROM) of dorsiflexion/plantarflexion was measured. Patients also completed the self-administered foot evaluation questionnaire (SAFE-Q) and the Japanese Society for Surgery of the Foot (JSSF) ankle/hindfoot score preoperatively and at the final follow-up.

          Results: No postoperative complications related to wound healing were observed even after the early rehabilitation program. The duration of hospitalization was shorter (23.5 days) than our previous experience after a conventional rehabilitation program (36-38 days). ROM for both dorsiflexion (from 4.6° to 16.5°; p=0.002) and plantarflexion (from 27.7° to 37.7°; p=0.019) increased significantly, and all indices of the SAFE-Q score and the JSSF score showed highly significant improvement.

          Conclusions: An early rehabilitation program was feasible and safe following the modified anterolateral approach. Although these points were confirmed with a cemented TAA system at present, further innovations in postoperative rehabilitation after TAA are expected.

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          Most cited references48

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          Investigation of the freely available easy-to-use software ‘EZR' for medical statistics

          Y Kanda (2012)
          Although there are many commercially available statistical software packages, only a few implement a competing risk analysis or a proportional hazards regression model with time-dependent covariates, which are necessary in studies on hematopoietic SCT. In addition, most packages are not clinician friendly, as they require that commands be written based on statistical languages. This report describes the statistical software ‘EZR' (Easy R), which is based on R and R commander. EZR enables the application of statistical functions that are frequently used in clinical studies, such as survival analyses, including competing risk analyses and the use of time-dependent covariates, receiver operating characteristics analyses, meta-analyses, sample size calculation and so on, by point-and-click access. EZR is freely available on our website (http://www.jichi.ac.jp/saitama-sct/SaitamaHP.files/statmed.html) and runs on both Windows (Microsoft Corporation, USA) and Mac OS X (Apple, USA). This report provides instructions for the installation and operation of EZR.
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            Understanding the role of immune regulation in wound healing.

            The immune system plays an integral role in successful wound healing. In addition to contributing to host defenses and inflammation, immune cells are critical regulators of wound healing through the secretion of cytokines, lymphokines, and growth factors. We review the mechanisms by which the immune system regulates wound healing.
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              Comparison of Disease Activity Score (DAS)28- erythrocyte sedimentation rate and DAS28- C-reactive protein threshold values.

              To estimate the disease activity score (DAS)28-C-reactive protein (CRP) threshold values that correspond to DAS28-erythrocyte sedimentation rate (ESR) values for remission, low disease activity and high disease activity in patients with rheumatoid arthritis. DAS28 data were analysed using a large observational study (Institute of Rheumatology Rheumatoid Arthritis) database of 6729 patients with rheumatoid arthritis. Firstly, the relationship between the DAS28-ESR and the DAS28-CRP values was analysed. Secondly, the best DAS28-CRP trade-off values for each threshold were calculated using receiver operating characteristic (ROC) curves. The correlation coefficient of ESR versus CRP was 0.686, whereas that of DAS28-ESR versus DAS28-CRP was 0.946, showing the strong linear relationship between DAS28-ESR and DAS28-CRP values. DAS28-CRP threshold values corresponding to remission, low disease activity and high disease activity were 2.3, 2.7 and 4.1, respectively. The sensitivity and specificity from the ROC curves were gradually reduced as DAS28 values became lower. This study showed that DAS28-CRP and DAS28-ESR were well correlated, but the threshold values should be reconsidered. As the results were derived from only Japanese patients, it is essential to compare DAS28-CRP threshold values in people of other ethnic groups.

                Author and article information

                Journal
                Cureus
                Cureus
                2168-8184
                Cureus
                Cureus (Palo Alto (CA) )
                2168-8184
                9 December 2024
                December 2024
                : 16
                : 12
                : e75398
                Affiliations
                [1 ] Orthopaedic Surgery, National Hospital Organization, Osaka Minami Medical Center, Kawachinagano, JPN
                [2 ] Orthopaedic Surgery, Graduate School of Medicine, Osaka University, Suita, JPN
                [3 ] Musculoskeletal Regenerative Medicine, Graduate School of Medicine, Osaka University, Suita, JPN
                [4 ] Orthopaedic Surgery/Rheumatology, Osaka Rosai Hospital, Sakai, JPN
                Author notes
                Article
                10.7759/cureus.75398
                11710851
                39781174
                56231f64-184b-47dd-b097-effa1294e667
                Copyright © 2024, Okamura et al.

                This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 9 December 2024
                Categories
                Physical Medicine & Rehabilitation
                Orthopedics

                early full-weight bearing exercise,early range of motion (rom) exercise,early rehabilitation program,total ankle arthroplasty (taa),wound healing

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