Hiroyoshi Yoshinami , MD, PhD 1 , Masanobu Shinogami , MD, PhD 2 , Ryoji Kagoya , MD 2 , Masato Nakashima , MD 1 , Isao Wada , MD, PhD 1 , Tutumiuchi Katuhiro , MD 1 , Tetsuo Ikezono , MD, PhD 1 , Yasuhiro Kase , MD, PhD 1 , Makoto Nagata , MD, PhD 3
17 February 2012
It is said that the chronic rhinosinusitis influences the lower respiratory airway and there is a report that a tendency to increase the eosinophilic rhinosinusitis later, but they are still unknown.
We divided the chronic rhinosinusitis patients with the adaptation of the operation into 4 groups and exaed whether there was a difference in the respiratory function, exhaled NO, and the number of the blood eosinophil.
Comparing these 4 groups, it was the worst on the respiratory function (one second rate) in the group with nasal polyps and without nasal allergy. It was recognized the connection between the respiratory function and the presence of the nasal polyps. It was possible that the exhaled NO became the index to the lower airway inflammation.