242 The Examination of the Association between the Chronic Rhinosinusitis and the Inflammation of the Lower Respiratory Airway by Using the Exhaled Nitric Oxide (NO) and the Respiratory Function Test

Abstract

Background

It is said that the chronic rhinosinusitis influences the lower respiratory airway and there is a report that a tendency to increase the eosinophilic rhinosinusitis later, but they are still unknown.

Methods

We divided the chronic rhinosinusitis patients with the adaptation of the operation into 4 groups and exaed whether there was a difference in the respiratory function, exhaled NO, and the number of the blood eosinophil.

Object

29 patients with chronic rhinosinusitis who planned the endonasal sinus surgery.

Results

Comparing these 4 groups, it was the worst on the respiratory function (one second rate) in the group with nasal polyps and without nasal allergy. It was recognized the connection between the respiratory function and the presence of the nasal polyps. It was possible that the exhaled NO became the index to the lower airway inflammation.

Conclusions

We classified the chronic rhinosinusitis and evaluated the lower airway function. It helps the pathologic understanding of the chronic rhinosinusitis. And it leads to understand of the influence on the lower airway inflammation.