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      Free Circulating Magnesium and Renal Magnesium Handling during Acute Metabolic Acidosis in Humans

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          Ion-selective electrodes have been designed for determining the ionized concentration of magnesium in blood, the biologically active form of this ion. The effect of acute acidosis induced by ammonium loading on circulating and urinary magnesium was investigated in 11 volunteers. No changes in plasma total and ionized magnesium were noted following administration of ammonium chloride. On the contrary, administration of ammonium chloride increased the plasma free magnesium fraction and the urinary magnesium excretion. The study demonstrates that the hypermagnesiuria induced by acute acidosis is not caused by ionized hypermagnesemia and supports the theory that acidosis decreases the circulating magnesium fraction that is bound to proteins.

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          Photometric determination of nitrogen. Wet incineration followed by formation of indophenol blue with salicylate/hypochlorite

           K Lauber (1976)

            Author and article information

            Am J Nephrol
            American Journal of Nephrology
            S. Karger AG
            June 1998
            06 May 1998
            : 18
            : 3
            : 233-236
            Departments of a Pediatrics and b Clinical Chemistry, University of Bern, Switzerland
            13342 Am J Nephrol 1998;18:233–236
            © 1998 S. Karger AG, Basel

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            Page count
            Figures: 1, Tables: 1, References: 24, Pages: 4
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            Clinical Study

            Cardiovascular Medicine, Nephrology

            Magnesium, Kidney, Calcium, Acidosis, metabolic


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