Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987).

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Abstract

The incidence of type 1 diabetes mellitus (T1DM) is increasing globally, and as a consequence, more patients are affected by microvascular complications such as diabetic retinopathy (DR). The aim of this study was to elucidate possible associations between diabetes-related single-nucleotide polymorphisms (SNP) and the development of DR.

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Author and article information

Journal

Journal ID (iso-abbrev): Graefes Arch. Clin. Exp. Ophthalmol.

Title: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Publisher: Springer Nature America, Inc

ISSN (Electronic): 1435-702X

ISSN (Print): 0721-832X

Publication date (Electronic): Nov 2015

Volume: 253

Issue: 11

Affiliations

[1 ] Department of Peadiatrics, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.

[2 ] Department of Peadiatrics, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark. kristian.sandahl@regionh.dk.

[3 ] Department of Ophthalmology, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.

[4 ] The Clinical Research Institute, University of Southern Denmark, Odense, Denmark.

[5 ] OPEN Odense Patient data Explorative Network, Odense University Hospital, Odense, Denmark.

[6 ] NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.

[7 ] Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Article

Publisher Item ID: 10.1007/s00417-015-3118-8

DOI: 10.1007/s00417-015-3118-8

PubMed ID: 26245339

SO-VID: 56e0c5bf-e7dd-420e-8c82-8b1643986069

History

Keywords: CTSH/rs3825932,Diabetic retinopathy,ERBB3/rs2292239,Proliferative diabetic retinopathy,SNPs,Type 1 diabetes mellitus

Data availability:

Keywords: CTSH/rs3825932, Diabetic retinopathy, ERBB3/rs2292239, Proliferative diabetic retinopathy, SNPs, Type 1 diabetes mellitus

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