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Finding their way: themes in germ cell migration
October 2016
October 2016
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Abstract
<p class="first" id="P2">Embryonic germ cell migration is a vital component of the
germline lifecycle. The
translocation of germ cells from the place of origin to the developing somatic gonad
involves several processes including passive movements with underlying tissues, transepithelial
migration, cell adhesion dynamics, the establishment of environmental guidance cues
and the ability to sustain directed migration. How germ cells accomplish these feats
in established model organisms will be discussed in this review, with a focus on recent
discoveries and themes conserved across species.
</p>