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      Megacystis-microcolon-intestinal hypoperistalsis syndrome: A visceral myopathy

      , , , ,

      Journal of Pediatric Surgery

      Elsevier BV

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          Abstract

          Two newborn infants with megacystis-microcolon-intestinal hypoperistalsis syndrome are described. Review of the literature revealed twenty previously reported cases of this syndrome. Electron microscopic examination of the ileum and urinary bladder showed vacuolar degenerative changes in the smooth muscle cells with abundant amount of connective tissue between the muscle cells. These ultrastructural findings suggest that a degenerative disease of smooth muscle may be the cause of megacystis microcolon intestinal hypoperistalsis syndrome.

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          Author and article information

          Journal
          Journal of Pediatric Surgery
          Journal of Pediatric Surgery
          Elsevier BV
          00223468
          February 1983
          February 1983
          : 18
          : 1
          : 64-69
          Article
          10.1016/S0022-3468(83)80275-9
          6834228
          © 1983

          https://www.elsevier.com/tdm/userlicense/1.0/

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