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Diabetes and outcomes following guided de-escalation of antiplatelet treatment in acute coronary syndrome patients undergoing percutaneous coronary intervention: a pre-specified analysis from the randomised TROPICAL-ACS trial.
Ralph Hein
1 ,
Lisa Gross ,
Dániel Aradi ,
Johannes Rieber ,
Martin Hadamitzky ,
Béla Merkely ,
Zenon Huczek ,
Hüseyin Ince ,
Astrid Hummel ,
Monika Baylacher ,
Steffen Massberg ,
Dietmar Trenk ,
Dirk Sibbing
August 09 2019
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Abstract
A guided de-escalation of P2Y12 inhibitor treatment is considered an alternative treatment strategy in ACS patients undergoing PCI. However, the safety and efficacy of this strategy may differ in diabetic vs non-diabetic patients. The aim of this study was to compare the outcomes of platelet function testing (PFT)-guided de-escalation of dual antiplatelet therapy (DAPT) in ACS patients with and without diabetes mellitus.