Blog
About

13
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Fatigue, depression, and physical impairment in multiple sclerosis

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Background: Fatigue, depression, and physical impairment are common among multiple sclerosis (MS) patients. The aim of this study was to determine the relationship between depression, physical impairment, and fatigue in an Iranian MS cohort.

          Methods: Fifty consecutive relapsing-remitting MS patients and 50 age- and sex-matched healthy controls (HCs) were recruited from Sina Rehabilitation Clinic, Tehran, Iran. The depression substance of Hospital Anxiety and Depression Scale (HADS), Expended Disability Status Scale, and Fatigue Severity Scale questionnaires were used to assess depression, physical impairment, and fatigue, respectively.

          Results: This study included 38 (76%) females and 12 (24%) males in both patients and HC groups. The depression substance of the HADS in MS and HCs showed a mean value of 1.92 ± 0.80 and 1.17 ± 0.38, respectively (P < 0.001). Pearson’s correlation analyses showed that in the MS group depression was associated with fatigue (r = 0.54, P = 0.01), but not with physical impairment (r = 0.16, p = 0.01), while fatigue was associated with both depression (r = 0.54, P = 0.01) and physical impairment (r = 0.36, P = 0.01). Depression in HCs group was also associated with fatigue (r -0.64, P = 0.01).

          Conclusion: Fatigue is associated with both depression and physical impairment, and an intervention in one of these conditions might improve others.

          Related collections

          Most cited references 12

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

          New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in some circumstances dissemination in space and time can be established by a single scan. These revisions simplify the Criteria, preserve their diagnostic sensitivity and specificity, address their applicability across populations, and may allow earlier diagnosis and more uniform and widespread use. Ann Neurol 2011
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The Hospital Anxiety and Depression Scale (HADS): translation and validation study of the Iranian version

            Background The Hospital Anxiety and Depression Scale (HADS) is a widely used instrument to measure psychological morbidity in cancer patients. This study aimed to translate and test the reliability and validity of the Iranian version of the HADS. Methods The English language version of the HADS was translated into Persian (Iranian language) and was used in this study. The questionnaire was administered to a consecutive sample of 167 breast cancer patients and statistical analysis was performed to test the reliability and validity of the HADS. Results In general the Iranian version of the HADS was found to be acceptable to almost all patients (99%). Cronbach's alpha coefficient (to test reliability) has been found to be 0.78 for the HADS anxiety sub-scale and 0.86 for the HADS depression sub-scale. Validity as performed using known groups comparison analysis showed satisfactory results. Both anxiety and depression sub-scales discriminated well between sub-groups of patients differing in clinical status as defined by their disease stage. Conclusion This preliminary validation study of the Iranian version of the HADS proved that it is an acceptable, a reliable and valid measure of psychological distress among cancer patients.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Fatigue in multiple sclerosis is related to disability, depression and quality of life.

              Fatigue in multiple sclerosis is a frequent and disabling symptom that can interfere in daily functioning. The aim of this study is to demonstrate the relationship between fatigue and disability, disease course, depression and quality of life. We administered French valid versions of the Fatigue Impact Scale (EMIF-SEP), the short form of the Beck depression inventory (13 items) and the SF-36 to 237 out of 312 patients with clinically definite multiple sclerosis with EDSS
                Bookmark

                Author and article information

                Journal
                Iran J Neurol
                Iran J Neurol
                IJNL
                Iranian Journal of Neurology
                Iranian Neurological Association (Tehran, Iran )
                2008-384X
                2252-0058
                3 April 2014
                : 13
                : 2
                : 105-107
                Affiliations
                [1 ]Department of Clinical Sciences, School of Medicine, Tehran University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
                [2 ]Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
                [3 ]Department of Medical Sciences, School of Medicine, Medical Students’ Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
                Author notes
                Corresponding Author: Azam Shahvarughi Farahani ot_farahani@ 123456yahoo.com
                Article
                IJNL-13-105
                4187328
                Copyright © 2014 Iranian Neurological Association, and Tehran University of Medical Sciences

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License, ( http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                Categories
                Short Communication

                Comments

                Comment on this article