Blog
About

  • Record: found
  • Abstract: found
  • Article: not found

Telfairia occidentalis extract stabilizes human erythrocyte membranes.

Nigerian quarterly journal of hospital medicine

Cucurbitaceae, chemistry, Plant Leaves, pharmacology, Plant Extracts, Phytotherapy, Nigeria, In Vitro Techniques, Hypolipidemic Agents, Humans, drug effects, Erythrocyte Membrane

Read this article at

ScienceOpenPubMed
Bookmark
      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

      Abstract

      In addition to being a widely consumed vegetable in West Africa, the leaves extract of Telfairia occidentalis is believed to have beneficial health effects and is used in tradomedical preparations. The effect of saline extract of T. occidentalis leaves on sickle and normal erythrocytes membrane stability was investigated. Human erythrocytes exposed to hypotonic and heat stress, by incubation in a buffered hypotonic medium at 56 degrees C, were stabilized by the extract in a doze dependent manner. The maximum stability was 72.3 +/- 3.1% and 55.0 +/- 4.1% for the sickle and normal erythrocytes membrane respectively (p < 0.0001). This study indicates that T. occidentalis has human erythrocyte membrane stabilizing activity. In addition the marked difference in the observed effect between the normal and sickle erythrocytes membranes suggests that pharmacogenetic factors may be involved in the response to herbal preparations.

      Related collections

      Author and article information

      Journal
      18318107

      Comments

      Comment on this article