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      Management of Wilms tumors in Drash and Frasier syndromes.

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          Abstract

          Children with WT1 gene-related disorders such as Denys-Drash syndrome (DDS) and Frasier syndrome (FS) are at increased risk of Wilms tumor and end-stage renal disease. We investigated whether Wilms tumors in these patients displayed a specific phenotype or behavior and whether nephron-sparing surgery was beneficial.

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          Author and article information

          Journal
          Pediatr Blood Cancer
          Pediatric blood & cancer
          Wiley
          1545-5017
          1545-5009
          Jan 2009
          : 52
          : 1
          Affiliations
          [1 ] Department of Pediatric Surgery, AP-HP, Hôpital Armand Trousseau, Paris, France. frederic.auber@trs.aphp.fr
          Article
          10.1002/pbc.21759
          18816692
          5855485f-5d74-4c14-82c9-57f2b4fb329c
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