Critical appraisal of network meta-analyses evaluating the efficacy and safety of new oral anticoagulants in atrial fibrillation stroke prevention trials.

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Abstract

To critically appraise published network meta-analyses (NMAs) evaluating the efficacy or safety of the new oral anticogulants (NOACs) dabigatran, rivaroxaban, and apixaban for the prevention of stroke in patients with nonvalvular atrial fibrillation (AF).

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Journal

Journal ID (iso-abbrev): Value Health

Title: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

ISSN (Electronic): 1524-4733

ISSN (Print): 1098-3015

Publication date (Electronic): Mar 2015

Volume: 18

Issue: 2

Affiliations

[1 ] Mapi, Health Economics and Outcomes Research, Toronto, ON, Canada. Electronic address: scope@mapigroup.com.

[2 ] Corporate Division Medicine, TA Cardiology, Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim, Germany; Center of Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.

[3 ] Boehringer Ingelheim, Paris, France.

[4 ] Medical Data Services, Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim, Germany.

[5 ] Tufts University School of Medicine, Boston, MA, USA.