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      Impaired Taste Acuity in Patients with Diabetes mellitus on Maintenance Hemodialysis

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          Aims: It has been reported that taste acuity for the four primary tastes, sour, sweet, salty and bitter, is impaired in hemodialysis (HD) patients. However, there have been no studies reported on taste acuity of diabetic HD patients. The present study aimed to quantify and compare the taste acuity of diabetic and non-diabetic HD patients, and further to determine if there were correlations between diminished taste acuity and certain blood serum parameters typically askew in hemodialysis patients. Methods: In a test group of 24 diabetic and 24 non-diabetic HD patients matched for age, body mass index and duration of HD, taste acuity for the four tastes was determined by asking patients to identify them at varying concentrations. Results: Statistical analyses indicate that bitter and total taste acuity were significantly impaired in diabetic HD patients. In diabetic HD patients, correlation was found between sweet, salty or total taste acuity and blood urea nitrogen or normalized protein catabolic rate. Conclusions: We conclude that taste acuity is partially impaired in diabetic HD patients, and suggest this contributes to reduced appetite, leading to malnutrition and poor prognoses.

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          Author and article information

          Nephron Clin Pract
          Nephron Clinical Practice
          S. Karger AG
          June 2003
          17 November 2004
          : 94
          : 2
          : c46-c50
          aKidney Center, Saiseikai Yahata Hospital, Kitakyushu, and bDivision of Nephrology, Department of Internal Medicine, Saga Medical School, Saga, Japan
          71281 Nephron Clin Pract 2003;94:c46–c50
          © 2003 S. Karger AG, Basel

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          Page count
          Figures: 2, Tables: 2, References: 21, Pages: 1
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/71281
          Original Paper

          Cardiovascular Medicine, Nephrology

          Malnutrition, Diabetes mellitus, Taste acuity, Hemodialysis


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